A vampire in the East Village picks up women, and while having sex with them kills them and drinks their blood. Meanwhile, a young Puerto Rican guy begins searching the Village for his sister, who is one of the vampire's victims.
Jo's world is thrown into utter disarray when her wife Amanda passes away and she starts chasing a dream that she and Amanda had once shared - starting a family together. Jo asks her late wife's brother, Jamie, to be her sperm donor and craziness ensues.
A couple move into a bad apartment in a bad neighborhood in New York. The apartment contains a refrigerator, which is the only thing they like in the place. However, they slowly discover that the refrigerator is a monster which kills people in gruesome ways and then sends them to hell. The refrigerator is already gaining mind control over the husband. What will happen?