To save the family business, two ne’er-do-well traveling salesmen hit the road with disastrously funny consequences.
Frank Drebin is persuaded out of retirement to go undercover in a state prison. There he has to find out what top terrorist, Rocco, has planned for when he escapes. Adding to his problems, Frank's wife, Jane, is desperate for a baby.
They used to run the country. Now they're running for their lives! Two on-the-lam former Presidents of the United States. Framed in a scandal by the current President and pursued by armed agents, the two squabbling political foes plunge into a desperately frantic search for the evidence that will establish their innocence.
Drew is an assistant director of personnel in a Cleveland department store and he has been stuck there for ten years. Other than fighting with co-worker Mimi, his hobbies include drinking beer and not being able to get dates. To make a few extra bucks he has a micro-brewery going in his garage with his buddies.