In 1879, the British suffer a great loss at the Battle of Isandlwana due to incompetent leadership.
A Miami cop finds out his wife has a female lover, and he begins to have an affair with his female partner. Meanwhile, a voodoo demon from Africa arrives among Miami's Nigerian community and begins decapitating some people and possessing others--including the cop's wife.
New York City is in a panic caused by an insane murderer; Maria, a police officer is entrusted with the case; to do this, she pretends to be a prostitute. One night, she meets a possible suspect who holds her and her partner hostage.
A young woman goes to teach at the Ravenscroft Institute, a spooky old girls' school overrun by ants and staffed by some unusual types. Spurred on by a series of horrific hallucinations, she begins to investigate the mysterious disappearances of several students.