Inventor Goro Ibuki creates a humanoid robot named Jet Jaguar. It is soon seized by an undersea race of people called the Seatopians. Using Jet Jaguar as a guide, the Seatopians send Megalon as vengeance for the nuclear tests that have devastated their society.
The film deals with the recruitment of race car driver Jiro Miki (Masao Kusakari) and his dog, Caesar, to a group of people who use ESP, psychokinesis, and other special mental abilities to fight crime.