A pharmaceutical scientist creates a pill that makes people remember their happiest memory, and although it's successful, it has unfortunate side effects.
Sydney Fox is a professor and globe-trotting "relic hunter" who looks for ancient artifacts to return to museums and/or the descendants of the original owner. She is aided by her linguistic assistant Nigel and occasionally by her somewhat air-headed secretary Claudia. She often ends up battling rival hunters seeking out artifacts for the money.
Junior reporter Frank Hardy and Joe, his computer-hacker brother, work together to crack mysteries.