A mother discovers that her 14-year-old daughter Yumi has leukemia and only six months to live. She decides to keep the information secret and pushes her past tutor Akira, now a university student, to reconnect with her.
The loyal Sōma clan samurai Tange Samanosuke is attacked and mutilated as the result of a betrayal, losing his right eye and right arm. He then begins to lead the life of a nihilistic ronin, using the pseudonym Sazen.