More than a dozen Angelenos navigate Valentine's Day from early morning until midnight. Three couples awake together, but each relationship will sputter. A grade-school boy wants flowers for his first true love. Two high school seniors plan first-time sex at noon. A TV sports reporter gets the assignment to find romance in LA. A star quarterback contemplates his future. Two strangers meet on a plane. Grandparents, together for years, face a crisis. An 'I Hate Valentine's Day' dinner beckons the lonely and the lied to.
Having left behind Seattle Grace Hospital, renowned surgeon Addison Forbes Montgomery moves to Los Angeles for sunnier weather and happier possibilities. She reunites with her friends from medical school, joining them at their chic, co-op, Oceanside Wellness Center in Santa Monica.