A single father and his children come to Little Bigfoot's rescue when a wealthy landowner hunts him down, hoping to use him as a profitable circus attraction.
After the death of her best friend Izzy, Anna focuses all her attention on Booger, the stray cat which she and Izzy took in. When Booger bites her, she begins to undergo a strange transformation.
Detectives Nick O'Malley and Kate Benson work in Special Unit 2, a secret precinct of the Chicago Police Department whose sole charge is to protect the city's citizens from Links, a malicious paranormal species that is the missing link between man and beast.