In a desolate future ruled by a totalitarian city-state known as Jesus Town, a leather-clad motorcyclist cyborg awakens from imprisonment to wage war against a regime that preaches peace through control.
Intergalactic bounty hunters Iria and Bob return to track down an ancient mystical relic. When a second Zeiram unit shows up and goes berserk, it takes all of Iria's resources to survive a deadly game of cat-and-mouse with the fearsome space creature.
A detective solves the puzzle box that releases the diabolical demon, Pinhead. As those around him begin to meet tragic fates, he sets out to conquer the horrifying villain.