Mandharam begins with the all too familiar trope - the schoolboy who spends his days dreaming about his childhood sweetheart and classmate, who, at the end of school, lets him know that she has a 'muracherukkan'.
Sudhakaran, a seventy-year-old man moulded by a male centric society from his childhood is a male chauvinist by nature. He gets to face situations where the society and his family questions his attitude towards opposite sex.
Vishnu decides to go to a palace as a fake veterinary doctor to earn money so as to clear his debts. But he finds several problems coming his way.
Ambu, a college student, develops romantic feelings for a woman he sees at a bus stop. However, things get complicated before he can profess his love to her.
