A student's premonition of a deadly rollercoaster ride saves her life and a lucky few, but not from death itself – which seeks out those who escaped their fate.
A reporter witnesses a brutal murder and becomes entangled in a mystery involving a pair of twins.
Dr. Gregory House, a drug-addicted, unconventional, misanthropic medical genius, leads a team of diagnosticians at the fictional Princeton–Plainsboro Teaching Hospital in New Jersey.