While an empowered and wiser Betty works hard on rebuilding her relationship with her teenage daughter Mila, her relationship with Armando begins to deteriorate, making her question if she made the right decision 20 years ago.
Diagnosed with a terminal illness, Macarena turns her chronic hypochondria into a quest for authenticity, even as her handsome doctor hides a secret.
Betty and Armando face new challenges as leaders of Ecomoda, a company in crisis. Between rivalries, betrayals, and the return of the unforgettable "Ugly Quarters," they must balance their family life while fighting to save the company's future.
Gertrudis and Armida are two young sisters with completely different personalities who learn to support each other after becoming orphans and being taken under the care of their aunt Luzmila, who denies them any kind of love. Between their innocence and their audacity, the two young women plan to escape, but everything goes wrong, they end up separated and thinking that the other one has died. It will take two decades for these two sisters to reunite.