In the world of the Pandyas, chaos is the norm and laughter is the solution to every problem. Just as the name suggests, 'Bushirt T-shirt' highlights two diverse ideologies between parents and their children along with the drama and emotions that follow. In an unexpected series of events, the Pandya's navigate their way through comic twists and entertaining turns in their quest to overcome their differences.
Raghav, a supermarket employee, and Meera, a journalist fall in love, marry and await their first child's arrival. Their lives take an unexpected turn when they're involved in an accident, leaving Raghav hospitalized in a intensive care.
Yash and Pooja are a newly wed couple who are off to their honeymoon. Another couple, Shweta & Rishi arrive at the same resort. Will there be a connection between these people? The tangle of relationships, true love, the journey of the difference between illusion and reality is Room No. 420.
