In 1948 Manhattan, a diverse group of people are committed to making the fledgling Empire Network a success. Among them: a naive young woman who's hired as a script girl; an idealistic programmer; and an aspiring director who hopes to make Empire "the network that takes risks and makes new stars." Then there's Empire's president, an eccentric scientist whose bride raises eyebrows at the network.
When petty criminal Earl Hickey wins the lottery, he sets off on a quest to repair his questionable karma.
An elite team of medical experts of the National Institutes of Health investigates unusual public-health crises, such as sudden outbreaks of serious and mysterious diseases.
James "Jimmy" Chance is a clueless 24-year-old who impregnates a serial killer during a one-night-stand. Earning custody of his daughter after the mother is sentenced to death, Jimmy relies on his oddball but well-intentioned family for support in raising the child.
