A village is hounded by an unknown disease, decimating its population. The village priest prophesies that God's avatar will save them. Siddha goes in search of this supernatural potential and finds it in Seetarama Raju, a cab driver.
During a visit to her hometown, Arundhati learns that she looks like her great-grandmother, Jejamma. Soon, Jejamma's battles become her own as she fights a black magician who wants to kill her.