Dr. Pontianak is about Dr. Vivy, a 26-year-old medical trainee who wakes up one day with injuries and a nail behind her neck. Strangely, she develops a craving for blood instead of fearing it.
After her failed suicide attempt, the depressed teenager girl is sent to a prison school, where she grows close to a boy with Bipolar Disorder, forcing her to re-evaluate and find ways out to end her suffering.