In the near future, mental time traveling will be invented. A hitman will use this untested technology to prevent the murder of an innocent person caused by a conflicted gangster.
Hit by the realization that his hustle is taking him nowhere, Johnny is on the verge of giving up boxing when nurse Ava gives him a much-needed nudge into trying again.
Al is concerned for his sister Edie, who starts to realize she's missing something meaningful in her free-spirit lifestyle.
Celestine gets hooked on a new dangerous drug, Nepenthe, and is visited by a mysterious woman named Irene who subtly pushes her towards madness. Meanwhile, Bob and his friends try to save Celestine from her newfound insanity.