Neglected by her husband during the pre-Christmas rush, Mrs. Claus takes the reindeer and sleigh out for a drive, only to end up stranded in the neighborhood of Manhattan's Lower East Side.
A lonely Frankenstein travels to 1930s Chicago to ask groundbreaking scientist Dr. Euphronious to create a companion for him. The two revive a murdered young woman and The Bride is born. But what ensues is beyond what either of them imagined.