RISE 143 took place on November 14, 2020, at Korakuen Hall in Tokyo, Japan. In the main event, super flyweight champion Kazuki Osaki defeated Shoot Boxing bantamweight champion Kyo Kawakami by unanimous decision. In the semifinal, Takumi Sanekata earned a future title shot with a decision win over Taplon Hades Workout. The card also featured a retirement exhibition match for Shota Takitani.
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