In this first film of the Lone Wolf and Cub series, adapted from the manga by Kazuo Koike, we are told the story of the Lone Wolf and Cub's origin. Ogami Itto, the official Shogunate executioner, has been framed for disloyalty to the Shogunate by the Yagyu clan, against whom he now is waging a one-man war, along with his infant son, Daigoro.
In the sixth and final film of the Lone Wolf and Cub series, the final conflict between Ogami Itto and the Yagyu clan is carried out.
In the fourth film of the Lone Wolf and Cub series, Ogami Itto is hired to kill a tattooed female assassin and battles Retsudo, head of the Yagyu clan, and his son Gunbei.
In the fifth film of the Lone Wolf and Cub series, Ogami Itto is challenged by five warriors, each has one fifth of Ogami's assassin fee and one fifth of the information he needs to complete his assassination.
A Shogun who grew paranoid as he became senile sent his ninjas to kill his samurai. They failed but did kill the samurai’s wife. The samurai swore to avenge the death of his wife and roams the countryside with his toddler son in search of vengeance.
Gokudo Shimamura comes to blows with the Delinquent Boss who rolls into town with his motorcycle gang.
In the second film of the Lone Wolf and Cub series, Ogami Itto battles a group of female ninja in the employ of the Yagyu clan and must assassinate a traitor who plans to sell his clan's secrets to the Shogunate.
In the third film of the Lone Wolf and Cub series, Ogami Itto volunteers to be tortured by Yakuza to save a prostitute and is hired by their leader to kill an evil chamberlain.