The mice are on the loose after hours in a doctor's office, playing with the various pieces of medical apparatus. Susie Mouse is caged for research until her lover Johnnie frees her. A mouse orchestra plays a swinging wedding song. But throughout, a cat is stalking...
Literary characters come to life late at night in a bookshop, serenading Sniffles the mouse with swing music until the Frankenstein monster intrudes.
When Mama hen takes her chicks out to get breakfast, little Wilbur is soaked in a sudden rainstorm and comes down with a head cold. Mama puts him to bed, then goes back out to get the doctor. A conniving weasel, seeing Mama leave, disguises himself as a doctor and comes calling on the unattended chicks.
The peaceful passage of daily life in the Pacific Ocean is upended in a flash on March 1, 1954, with the first American nuclear test at Bikini Atoll. The far-reaching fallout forever changes the lives of the ocean’s cheerful inhabitants.
Herman the mouse attempts to break up the smarmy friendship between the cat and dog of the house in order to raid the icebox.
Woody is shooting pool at a farm house when one of his pool balls rolls into a nearby henhouse. He takes the ball back but must battle with the hen who thinks the woodpecker is taking one of her eggs. Woody makes several attempts to get the ball back from the protective poultry finally disguising himself as a macho continental rooster whom the hen falls for causing Woody to retrieve his ball. But it doesn't last long.
Yosemite Sam is trying to rob the train that Bugs Bunny is riding on, and the two face off in several different ways.
Tom and Jerry are sleeping outside during the day when a yellow bird wearing a red helmet lands on Tom, waking him up. Although the bird brushes Tom's torso off and reacts politely like "pardon me", Tom goes after the bird, catches it, and proceeds to beat it up.
When Jerry rustles cheese from the Dry Gulch General Store, Sheriff Mutt Dillin hires Tom, the fastest trap in the West.
When a bulldog tells Jerry to "just whistle" any time that he needs him, Tom's in for big trouble until he puts earmuffs on the mutt.
When a faithful police dog and his human police officer owner are injured together on the job, a harebrained but life-saving surgery fuses the two of them together and Dog Man is born. Dog Man is sworn to protect and serve—and fetch, sit and roll over. As Dog Man embraces his new identity and strives to impress his Chief, he must stop the pretty evil plots of feline supervillain Petey the Cat.
Mowgli, a fearless boy raised by wolves, embarks on his most daring adventure yet when he discovers his tiger cub friends are in danger of being captured by evil poachers. Never one to back down from a challenge, Mowgli unites his animal friends to prevent harm to one of the jungle’s own.
The final "canonical" episode of the series is a New Year Special.
Hare buys glasses at the store, on the way out Wolf lures him to his house. At home they want to drink juice from the new glasses, but the glasses start to break right in their hands. The episode raises the problem of poor quality splintering glasses.
The Coyote tries, with no success, to find a way across a gorge to reach the Road Runner on the other side.
After putting on the shoes from the store, the wolf chases the hare, but soon they both lose the shoes on the way. The issue raises the problem of poor quality shoes produced in the Soviet Union at that time.
After another failed series of attempts to catch the ever-elusive Road Runner with a grenade, a bow, a rope, invisible paint, and a gun disguised as a peep show, Wile E. Coyote uses a rocket to chase after the bird. The rocket goes off course, crashes through the earth and sends Wile E. to China where a Chinese Road Runner greets him.
Mickey, Minnie, Horace Horsecollar, and Clarabelle Cow go on a musical wagon ride until Peg-Leg Pete tries to run them off the road.
Bugs Bunny and Yosemite Sam duel with trains in an Old West shootout.
The chase continues between Tweety Bird and that persistant puddy tat, Sylvester. Tweety hides in a millinery store (where Granny happens to be shopping) and hides on a hat.