A computer expert embezzles half a million dollars and races off to Reno to start anew. Unfortunately, en route, he picks up a pair of hitchers and ends up entangled with a crazed couple who commandeer his car and leave him alone in the desert to die. As soon as he can, he hits the road to get revenge and to find his money before they do.
An anthology of five macabre short stories about hungry ghosts, comatose brain dead, a group of bright-eyed actors, an unscrupulous car salesman, and careless backpack tourists.
After FBI agent Frank Lacrosse believes his son was kidnapped by a notorious serial killer, he travels to Amarillo, Texas, where he believes the murderer is in hiding. Although officially taken off the case because of its personal significance to him, Frank continues to pursue the killer, causing concern for local sheriff Buck Olmstead. When another victim pops up at a nearby car garage, Frank knows that he is as close as he'll ever be to tracking down the elusive killer.
Following the arrest of her mother, Ramona, young Vanessa Lutz decides to go in search of her estranged grandmother. On the way, she is given a ride by school counselor Bob Wolverton. During the journey, Lutz begins to realize that Bob is the notorious I-5 Killer and manages to escape by shooting him several times. Wounded but still very much alive, Bob pursues Lutz across the state in this modern retelling of Little Red Riding Hood.
Taking a break from their dreary lives, close friends Thelma and Louise embark on a short weekend trip that ends in unforeseen incriminating circumstances. As fugitives, both women rediscover the strength of their bond and their newfound resilience.
Two young hitch-hikers on a spree of revenge.
Thomas hitchhikes from Hamburg to Munich where he meets his ex-girlfriend, Peggy. Thomas doesn't have a bed for the night and goes home with Peggy, not knowing that she and her four roommates have all made a strange pact.
While driving through the New Mexico Desert during a rainy night, college students Jim Halsey and his girlfriend Grace Andrews give a ride to a hitchhiker. While in their car, the stranger proves to be a psychopath threatening the young couple with a knife, but Jim successfully throws him out of the car. This sets off a chain of events that will change all of their lives forever.
Set in 1964, a three-day journey along Route 66 begins when Bobby Falls, a 19-year-old serial killer, hitches a ride with Jim Goodwin, a celebrity animal handler travelling with his precious cargo: his TV chimpanzee, Spanky.
When a young boy decides to hitchhike to get to a nearby village, he has no idea of the driver's true intentions.
A young woman stumbles into a nightmare land of hijacking and humiliation while driving cross-country from California to New York.
The life of Al Roberts, a pianist in a New York nightclub, turns into a nightmare when he decides to hitchhike to Los Angeles to visit his girlfriend.
A sadistic serial killer terrorizes a couple driving on a rural highway in Texas while killing numerous people and framing them for his killings.
Gifted but hot-headed sculptor Eric has a stormy, erotic, and star-crossed romance with a beautiful young woman named Olga.
In this Franco-Italian gangster parody, a shopkeeper on his way to an Italian holiday suffers a crash that totals his car. The culprit can only compensate his ruined trip by driving an American friend's car from Naples to Bordeaux, but as it happens to be filled with such contraband as stolen money, jewelry and drugs, the involuntary and unwitting companions in crime soon attract all but recreational attention from the "milieu".
Kowalski works for a car delivery service, and takes delivery of a 1970 Dodge Challenger to drive from Colorado to San Francisco. Shortly after pickup, he takes a bet to get the car there in less than 15 hours.
A young man is in a race against time as he searches for a cure after becoming infected with a virus that will eventually turn him into a blood-sucking vampire.
Zia, distraught over breaking up with his girlfriend, decides to end it all. Unfortunately, he discovers that there is no real ending, only a run-down afterlife that is strikingly similar to his old one, just a bit worse. Discovering that his ex-girlfriend has also "offed" herself, he sets out on a road trip to find her.
On their way to an afternoon on the lake, husband and wife Andrzej and Krystyna nearly run over a young hitchhiker. Inviting the young man onto the boat with them, Andrzej begins to subtly torment him; the hitchhiker responds by making overtures toward Krystyna. When the hitchhiker is accidentally knocked overboard, the husband's panic results in unexpected consequences.
Howard is mild-mannered and slightly simple-minded, with a habit of picking up teenage hitchhikers while driving his delivery routes. Sometimes the girls admit to being runaways, and if they claim to hate their mothers it drives Howard into a violent frenzy; his sister ran away from home years ago and was never heard from again, causing his desperate, addled mother to tighten her hold on him. Howard never remembers raping his victims or strangling them with wire coat hangers, though his boss does notice missed deliveries and late arrivals.