Raoul Duke and his attorney Dr. Gonzo drive a red convertible across the Mojave desert to Las Vegas with a suitcase full of drugs to cover a motorcycle race. As their consumption of drugs increases at an alarming rate, the stoned duo trash their hotel room and fear legal repercussions. Duke begins to drive back to L.A., but after an odd run-in with a cop, he returns to Sin City and continues his wild drug binge.
Joe and Paul Fabrini are Wildcat, or independent, truck drivers who have their own small one-truck business. The Fabrini boys constantly battle distributors, rivals and loan collectors, while trying to make a success of their transport company.
One evening, Hammer gives a ride to Christina, an attractive hitchhiker on a lonely country road, who has escaped from the nearby lunatic asylum. Thugs waylay them and force his car to crash. When Hammer returns to semi-consciousness, he hears Christina being tortured until she dies. Hammer, both for vengeance and in hopes that "something big" is behind it all, decides to pursue the case.
After a group of Texas teenagers leave prom night early and get into a car crash in the woods, they employ the aid of a nearby insurance agent, who calls in her tow truck-driving boyfriend, Vilmer Slaughter. Unfortunately for them, Vilmer is a sadistic killer with a mechanical leg who introduces them to his brother, Leatherface, and the rest of their twisted family.
The life of Al Roberts, a pianist in a New York nightclub, turns into a nightmare when he decides to hitchhike to Los Angeles to visit his girlfriend.
A sadistic serial killer terrorizes a couple driving on a rural highway in Texas while killing numerous people and framing them for his killings.
On a road trip across Italy, recent high school graduates Ira, Malin and Ka pick up the intriguing backpacker Zoe. As the four girls stumble across an abandoned village, they start to experiment with the limits of their newly found freedom, away from the expectations of their parents and teachers.
A young woman stumbles into a nightmare land of hijacking and humiliation while driving cross-country from California to New York.
Monette, a recently separated travelling book salesman tells his grim story to both a priest and a hitchhiker, looking for absolution.
American Neil Bowman is traveling through France when he meets British photographer Lila. They are hired by French land owner Duc de Croyter to escort a Hungarian scientist to New York. But they soon realize that the job is not a cushy number, and have to deal with a gang of kidnappers who will stop at nothing to get their hands on the scientist
An anthology of five macabre short stories about hungry ghosts, comatose brain dead, a group of bright-eyed actors, an unscrupulous car salesman, and careless backpack tourists.
In this fast-paced, noirish road movie, a computer expert embezzles half a million dollars and races off to Reno to start anew. Unfortunately, en route, he picks up a pair of hitchers and ends up entangled with a crazed couple who commandeer his car and leave him alone in the desert to die. As soon as he can, he hits the road to get revenge and to find his money before they do.
Susan has chosen a hermit's life on a dilapidated farm over the shallowness of her previous jet set modeling life. When Anton, a hunky courier, comes along to pick her up for an assignment on the French Riviera, he's so fascinated by Susan's odd assortment of house guests that he decides to stay with them for a couple of days.
Zia, distraught over breaking up with his girlfriend, decides to end it all. Unfortunately, he discovers that there is no real ending, only a run-down afterlife that is strikingly similar to his old one, just a bit worse. Discovering that his ex-girlfriend has also "offed" herself, he sets out on a road trip to find her.
Thomas hitchhikes from Hamburg to Munich where he meets his ex-girlfriend, Peggy. Thomas doesn't have a bed for the night and goes home with Peggy, not knowing that she and her four roommates have all made a strange pact.
While driving through the New Mexico Desert during a rainy night, college students Jim Halsey and his girlfriend Grace Andrews give a ride to a hitchhiker. While in their car, the stranger proves to be a psychopath threatening the young couple with a knife, but Jim successfully throws him out of the car. This sets off a chain of events that will change all of their lives forever.
Kowalski works for a car delivery service, and takes delivery of a 1970 Dodge Challenger to drive from Colorado to San Francisco. Shortly after pickup, he takes a bet to get the car there in less than 15 hours.
Matt, with the assistance of his new friend Riley, is moving out to Los Angeles California to fulfill his dream of making movies. Everything is off to a good start! That is until Matt's childhood best friend Chaps decides to crash the road trip and invite himself along. When old friends don't mix well with new friends, jealousy enters the picture. And if that wasn't enough to put a damper on the road trip, a menacing hitchhiker turns their world upside down leading to a maddening chase that spins wildly out of control.
On their way to an afternoon on the lake, husband and wife Andrzej and Krystyna nearly run over a young hitchhiker. Inviting the young man onto the boat with them, Andrzej begins to subtly torment him; the hitchhiker responds by making overtures toward Krystyna. When the hitchhiker is accidentally knocked overboard, the husband's panic results in unexpected consequences.
Taking a break from their dreary lives, close friends Thelma and Louise embark on a short weekend trip that ends in unforeseen incriminating circumstances. As fugitives, both women rediscover the strength of their bond and their newfound resilience.