Ben Sanderson, an alcoholic Hollywood screenwriter who lost everything because of his drinking, arrives in Las Vegas to drink himself to death. There, he meets and forms an uneasy friendship and non-interference pact with prostitute Sera.
Eight very different couples deal with their love lives in various loosely interrelated tales all set during a frantic month before Christmas in London.
Bill Parrish has it all - success, wealth and power. Days before his 65th birthday, he receives a visit from a mysterious stranger, Joe Black, who soon reveals himself as Death. In exchange for extra time, Bill agrees to serve as Joe's earthly guide. But will he regret his choice when Joe unexpectedly falls in love with Bill's beautiful daughter Susan?
In order to help bring Nazis to justice, U.S. government agent T.R. Devlin recruits Alicia Huberman, the American daughter of a convicted German war criminal, as a spy. As they begin to fall for one another, Alicia is instructed to win the affections of Alexander Sebastian, a Nazi hiding out in Brazil. When Sebastian becomes serious about his relationship with Alicia, the stakes get higher, and Devlin must watch her slip further undercover.
A small suburban town receives a visit from a castaway unfinished science experiment named Edward.
Caught in a bizarre and terrifying time warp, college student Tree finds herself repeatedly reliving the day of her murder, ultimately realizing that she must identify the killer and the reason for her death before her chances of survival run out.
Although strangers Sara and Jonathan are both already in relationships, they realize they have genuine chemistry after a chance encounter – but part company soon after. Years later, they each yearn to reunite, despite being destined for the altar. But to give true love a chance, they have to find one another again.
A high school slacker who's rejected by every school he applies to opts to create his own institution of higher learning, the South Harmon Institute of Technology, on a rundown piece of property near his hometown.
Ready for a night of legendary partying, three college students must weigh the pros and cons of calling the police when faced with an unexpected situation.
Barksdale University is typically a very safe place. However, tonight is a full moon and the new moon studies teacher Dr. Howell seems to be hiding something... But hey, that's not going to stop the biggest party on campus from happening at the sorority house!
An acclaimed college hoops coach is demoted to a junior varsity team after a public meltdown.
At a 1962 College, Dean Vernon Wormer is determined to expel the entire Delta Tau Chi Fraternity, but those troublemakers have other plans for him.
Gib, a beer-guzzling slob, and Alison, an uptight Ivy-Leaguer, are an unlikely duo stuck together on a cross-country trip during Christmas break. At first they get on each other's nerves but, as time passes, they find their divergent natures complement each other. Now they need to realize what they've already found before it's too late.
The Dean and Board of Flunk Well College are arguing with its football coach, Bergen, about the team's star player, Charlie McCarthy, who is the only reason the team is a winning one, but who isn't doing well academically and could be pulled from the team if his grades and behavior don't improve. In other words, Charlie is a dummy in more ways than one. Beyond other problems Coach Bergen has with Charlie concerning the coach's girlfriend Joan, Coach Bergen has to get Charlie prepared to pass an exam administered by the Dean. Instead of cheating like he usually does, Charlie has his own way of dealing with the exam.
When Erik Stifler realizes that he's the only Stifler family member who might graduate high school a virgin, he decides to live up to his legacy. After some well-meaning advice from Jim's dad, Erik's ready to take his chances at the annual and infamous Naked Mile race, where his devoted friends and some uninhibited sorority girls will create the most outrageous weekend ever.
Erik, Ryan, and Cooze start college and pledge the Beta House fraternity, presided over by none other than legendary Dwight Stifler. But chaos ensues when a fraternity of geeks threatens to stop the debauchery and the Betas have to make a stand for their right to party.
After being falsely accused of stealing the budget for their annual cocktail cruise, three very different fraternity brothers are kicked out of their dorm. In order to clear their name and to secure their future careers, the three dress up in drag and pledge the sorority next door where they learn a few valuable - and hilarious - lessons about themselves and the female species.
Barry B. Benson, a recent college graduate who wants more out of his life than making honey, decides to sue the human race after learning about the exploitation of bees at the hands of mankind. What will happen next?
Harvard Law student Oliver Barrett IV and music student Jennifer Cavilleri share a chemistry they cannot deny - and a love they cannot ignore. Despite their opposite backgrounds, the young couple put their hearts on the line for each other. When they marry, Oliver's wealthy father threatens to disown him. Jenny tries to reconcile the Barrett men, but to no avail.
After an Ithaca College student films his one-night stand with a beautiful sorority girl, he discovers one of his friends has accidentally mailed the homemade sex tape to his girlfriend in Austin. In a frenzy, he must borrow a car and hit the road in a desperate bid to intercept the tape.