Two jobless Americans convince a prospector to travel to the mountains of Mexico with them in search of gold. But the hostile wilderness, local bandits, and greed all get in the way of their journey.
In the latter half of the 19th century, gold is discovered in the Black Hills, sacred land of the Lakota people. Gold diggers, profiteers and adventurers flock to the region. Among them is the hard-hearted land speculator Bludgeon, who tries to expel the Lakota using brutal methods. Lakota warriors retaliate, and soon the gold diggers' town becomes a battlefield.
Mitch Robbins' 40th birthday begins quite well until he returns home and finds his brother Glen, the black sheep of the family, in his sofa. Nevertheless he is about to have a wonderful birthday-night with his wife when he discovers a treasure map of Curly by chance. Together with Phil and unfortunately Glen he tries to find the hidden gold of Curly's father in the desert of Arizona.
In order to make Tug Cardwell (William Phipps) sign over his rich gold claim to them, John Avery (Robert Shayne), Gypsy Avery (Veda Ann Borg) and Jackson (Marshall Reed) hire Bob Rankin (Douglas Fowley') to kidnap Tug's sweetheart Jane Whipple (Elaine Riley). Rankin hides Jane and then demands half the mine from the other crooks. Dave Saunders (Tim Holt) and Chito Rafferty (Richard Martin), friends of Tug's, find Jane and taker her to safety. The conspirators then shoot Rankin, capture Tug and force him to take them to his claim. Dave and Chito are close behind.
Sgt. Renfrew and Constable Kelly go aloft to search for a plane missing with a shipment of gold from the Yukon Mine Company. Inventor Speavy has devised a power ray which disrupts electrical impulses, and Morgan and his gang of crooks has brought in Prof. Lewis to increase the ray's range, telling him he's helping the government develop this new weapon. Speavy spills the beans to Prof. Lewis and his daughter Madeleine,and Morgan threatens to implicate them in his crimes unless they cooperate. Morgan kills Speavy when he tries to warn Renfrew, but when Madeleine stows away on board the doomed plane Renfrew is piloting, will the crooks be able to make Prof. Lewis use the power ray to bring the plane down?
The Durango Kid is a sort of Robin Hood of the West who helps the lovely Walters (who replaced Starrett's usual love-interest, Iris Meredith), the daughter of a homesteader, defeat the evil MacDonald who has been terrorizing the decent citizens with his gang of rustlers.
An army gold shipment and its escort vanish in the Ozarks, prompting accusations of theft and desertion but frontiersman Old Shatterhand and Apache chief Winnetou help solve the mystery of the missing army gold.
After striking gold in Alaska, the romantic George sends his womanizing partner Sam to bring his fiancée up from Seattle. When Sam finds that she has already married, he returns instead with Angel, a dancer originally from France.
When Temple's miners strike gold they send Jake to file the claim. Dana is in the Recorder's office and overhears. He and his men kill Jake and forge new deeds. Now owning everything Dana tries to kick the Temple group off their land. But Jack and sidekick Lucky are on hand and plan to help them fight back.
A widow hires an ex-gambler to retrieve gold bars from a sunken river boat in Colorado and discreetly return them to the Federal Mint, from where they had been stolen by her dead husband.
A part-Indian mining engineer looks for gold in an Arizona ghost town with his socialite bride.
A study in greed in which treasure hunters seek a shipment of gold buried in Death Valley.
The Durango Kid (Charles Starrett) returns to Ret Butte intending to sell his cattle ranch. Saloon owner, Duke Catlett (Lane Chandler) is the secret owner of a sheep flock which graze on the cattle lands--leaving them useless for cattle. A range war looms between the cattlemen and sheepherders.
Freight wagons are being stolen and ransomed back to their owners. Government agent Steve Langtry (and his alter ego the Durango Kid) is sent break up the Hood Gang that's behind the robberies.
Silver is being smuggled across the border and the secret passage goes through Betty Long's basement. When Steve arrives he gets tangled up with the rustlers who are now going to have the Durango Kid to contend with.
A major Indian uprising is expected and Wyoming military posts are alerted. Colonel Dennison is meeting with Chief Eagle and his son Running Wolf when Chief Eagle is mysteriously shot. Steve Holden, an agent for the government peace commission, with the aid of a wandering shoemaker, Smiley, discover the troubles and the Chief's murder have been instigated by Cronin, the regimental scout, for personal gain for he and his gang of outlaws.
Old Mike Brady built Brady Town and was a leader, but a bullet from an unknown assailant has ended his life. When the will is read, it leaves the bulk of the property to Kirk, the gambling son of Mike. This upsets Sam, the hard working son, but not gambler Full House who always beats Kirk at cards. But even the Sheriff is suspicious of the will, but he needs proof and the Durango Kid will find the proof.
Stage line owner Brent has his men robbing Halliday stages and when his manager Waring learns of it, Brent has him killed. Jeff Waring arrives and takes his uncle's job. He soon learns what's happening and the Durango Kid goes into action. This keeps Halliday going and gives them a chance to get the mail contract by winning the stagecoach race.
Steve Holden, a secret service agent, is suspended when his boss becomes suspicious of his activities as The Durango Kid. Can Steve prove his innocence?
When Sheriff Jeff Connor of Powder River cannot stop the crime wave, his young son, Larry, writes to the Durango Kid for aid. Taggart, the saloon owner, is the secret head of the outlaws, while Connor's brother Bill is in cahoots with him. Steve Randall, the Durango Kid, and his pal, Smiley Butterbean, arrive in time to stop a stagecoach holdup, and Steve is made a deputy sheriff. Taggart has one of his men, Slade, pose as the Durango Kid and while he is speaking to the townspeople, the rest of the outlaw gang pillages the town, and this somewhat damages the Durango Kid in the eyes of Larry and his sister Doris. Steve suggests that Sheriff Connor visit the government about a railroad project, and Taggart instructs Slade and the gang leader to kill Connor on his trip back.