A variety of predicaments arise to distract Dr. Kildare from his wedding to Nurse Mary Lamont.
Dr. Kildare treats and falls for impoverished ex-con Janet Healy, widow of a bank robber, who can't find her baby. Later she helps Kildare sew up gangster Hanlon in a tavern back room. Kildare pursues Janet and enlists Hanlon to help her; the gangster's solution, not surprisingly, is violent.
A medical school graduate takes an internship at a big city hospital, only to be subjected to a rigorous (and sometimes embarrassing) testing of his knowledge by the hospital's top dog, Dr. Leonard Gillespie.
Following an argument with his young protege, the curmudgeonly Dr. Gillespie dumps Jimmy Kildare in a street clinic, hoping to teach him a lesson. While working there Kildare meets pretty nurse Mary Lamont, and ends up treating a hoodlum with a gunshot wound. He purposely fails to write a report on it, and soon finds himself in a heap of trouble. Who else would come to his rescue but good old Dr. Gillespie?
Intern Kildare heals a millionaire's daughter and tricks Dr. Gillespie into taking a vacation.
An ice skater sues Kildare (Lew Ayres) for malpractice after his roadside first aid leaves her paralyzed.
Dr. Gillespie supports Kildare's crusade against their hospital's deal with a rival hospital.
Jimmy Kildare's impending nuptials are jeopardized by a diagnosis of possible epilepsy in his fiancee's brother.
A young doctor gives up big-city success to help his father set up a small-town clinic.
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Pep, a 13-year-old boy, is in love with a girl from his grandparents village, Sara Amat. One summer night, Sara disappears without a trace. After a few hours, Pep finds her hiding in his room. Although Pep knows that the entire town is looking for her, he agrees to her stay. Consequently, the boy will be forced to live a double life: he must lie to everyone while satisfying the Sara's demands.
As part of a brutal hazing ritual, a young frat pledge leads a wasted girl upstairs to swipe his v-card, only to discover getting lucky isn't so easy.
While parents, people of traditional rural values, are cooking blood sausage for the visit of daughter-in-law, Andriy, their son, tries to communicate the fact his fiancee is Jewish.