The music-happy Bosko and Honey take a car ride, but bad luck briefly interrupts their fun.
Wile E. Coyote, on his usual hunting rounds, spies Road Runner having a drink from a water fountain during his morning sprint.
It is Christmas in the Snake Bite Desert, and Road Runner is off on his usual sprint once again.
Wile E. Coyote (Starvingus loserus) uses a falcon disguise to catch Road Runner (Speed breaking recordus).
After failing to crush the bird with a boulder all by himself, Wile E. Coyote (Eternicus-failurus) attempts to catch Road Runner (Speedius-ludicrous) by using an ACME Clone-O-Matic.
Wile E. Coyote (Fallious-flatius) uses an ACME Weather Control Kit to try and catch Road Runner (Speedius-gonzalicus) through various weather-related tricks.
Bosko is a construction worker who impresses Honey by making music from everything in sight, including a decapitated mouse, a typewriter and a goat filled with hot air.
After Acme products fail him one too many times in his dogged pursuit of the Roadrunner, Wile E. Coyote decides to hire a billboard lawyer to sue the Acme Corporation.
Late at night, the mice come out and sing and play to the title tune, among others. That is, until the cat arrives, but he's quickly sent packing.
Among the strategies that fail in Wile E. Coyote's attempts to catch the Roadrunner: glue on the road, a giant rubber band, an outboard motor in a wash tub, and dressing in drag as a female Roadrunner.
A streetcar conductor, Foxy has adventures with a would-be passenger hippo, a cow blocking the tracks, and a runaway train while Foxy, his passengers, and some hobos sing the title song.
Bosko and Honey go on a picnic that ends badly.
Bosko fishes, and sings and dances with frogs. But two ladybugs use a wasp as an airplane, and a beehive and tree branch as a machine gun to drive him away.
Bosko and Honey yodel happily in the Alps until a series of disasters end with Honey rushing downriver on an ice floe.
Bosko joins a wacky fox hunt. But if the hunt worries anyone, it isn't the fox.
Bosko is shipwrecked on an island where he is chased by a lion and pursued by simian cannibals.
Foxy the Cop is trying to enforce the law in town, but dangerous drivers and strangers who also kidnap Roxy are making this difficult.
Bosko is a soda jerk, who gives poor service to a mouse and to his former schoolteacher. Later, he must contend with Honey's bratty Wilbur.
The old toymaker goes to sleep, and his toys immediately come to life and sing "Red-Headed Baby." A red-haired baby doll begins the song. She's soon joined by her sweetheart, a toy soldier named Napoleon. A spider briefly spoils the fun when he descends upon the toys and grabs the doll. It's up to Napoleon to save her.
Piggy and Fluffy have adventures on a riverboat and Uncle Tom is chased by skeletons promising to take him to Hallelujah Land.