Joe Cobb is suffering through a toothache as well as having to babysit his little brother Rupert who won't stop crying. Every effort to calm Rupert is undone by an immediate commotion to wake him up. Joe rocks him to sleep, but then the neighbor starts playing his bass fiddle. Joe then rocks the cradle so hard it falls apart, and he trips and stumbles moving Rupert to the baby carriage, which subsequently rolls down hill through traffic with Rupert and a neighbor's monkey enjoying the ride.
The gang goes digging for treasure in an old abandoned house against Kennedy the Cop's wishes.
While playing baseball, Mickey runs into the street to catch a fly ball and is struck by a car. When the gang visit him in the hospital they are appalled to find the ward populated by many other children injured in automobile accidents. The Our Gang kids resolve to do something about the problem, and thus the "1-2-3-Go Safety Society" is born.
Inspired by his soldier brother, Spanky decides to organize a military unit among his friends, collecting odds and ends for the war effort.
Froggy hatches a plan to get Mickey, Buckwheat, and himself sent home from school early so they can go fishing. When the plan backfires, the boys decide to play hooky the next day. At the fishing hole, there are plenty of lunkers just waiting for the bait, but the boys have some comic trouble. After Buckwheat finds a new way to catch fish, an old man gives them a life lesson. Will they keep fishing or change their ways?
Farina, Joe, and friends use dogs to power their "roadsters," but following a lesson from the head of the Be Kind to Animals Society, they make it their cause to rescue animals from bad treatment. Joe even manages to find patience for a nagging flea that persists in biting him. Meanwhile, Wheezer, who has been tormenting animals with his games, dreams that the animals have turned the tables on him.
Spanky and Alfalfa plot to play hooky so they can go fishing, by pretending that Alfalfa is sick and Spanky should stay with him while the parents are away. But Spanky's mom, knowing the truth, turns the tables by insisting they also watch Spanky's little brother. But taking care of little brother turns out to be more difficult than they expected.
Spanky and the gang discover a demonstration of a "human-like" robot named Volto and are inspired to create a robot themselves to do their chores for them. Slicker Walburn convinces them they will need "invisible rays" to bring it to life which he just happens to have to sell to them. As they rush off to get their money, Slicker gets Boxcar Smith to wear the robot's outer body so when he "brings" the robot to life, it will be Boxcar bringing it to life. The gang unsuspectedly gets their robot to mow the lawn at Froggy's house, but with a signal from Slicker, Boxcar runs amok and mows down everything in his path. Froggy gets to explain what happened to his parents who bust up the fraud and get the miscreants to work with the gang to clean up the mess.
Spanky and the Our Gang kids go to battle over pranks with a rival gang.
Nancy and Sluggo do their bit for the USO.
The gang wants Spanky to come out and play football, but he has to make sure his baby sister is asleep first.
To impress Darla, Alfalfa drinks a concoction of Butch's "dynamite" brew.
Alfalfa and the gang decide to turn to a life of crime, but Spanky tries to trick them with a fake burglary.
The kids from Our Gang have to attend a wedding, and they bring along their flea collection--which gets loose.
The gang is participating in a program sponsored by the Golden Age Dramatic League. They present their own fractured version of Quo Vadis. Things go from bad to worse when the neighborhood tough kids disrupt the show. The pie fight is given a new twist by use of some slow motion sequences.
While under a hypnotic spell, Alfalfa thinks he's one of the Three Musketeers and challenges Butch to a duel.
The kids go to the hospital to visit Darla, who's recovering from a tonsillectomy. Chaos soon ensues.
Darla pretends to like Butch, hoping to motivate Alfalfa into a better performance in the football game against Butch's team.
Alfalfa imagines himself as a western movie hero battling with Butch for Darla's heart.
Spanky and Alfalfa want to do a show based on the "Aladdin's Lamp" story with Darla in the cast, but Darla doesn't want to participate.