A brilliant but deranged neurosurgeon becomes obsessively fixated on a judge's daughter. With the help of an escaped criminal whose face he has surgically deformed, the mad man lures her, her father, and her fiancé to his isolated, castle-like home.
Following his forced retirement from an appalling rock band, Jason decides to vacation at Brittlehouse Manor, a health farm run by the leather-gloved, ex-Nazi scientist Dr. Storm. Along the way, Jason meets Judy, also on her way to Brittlehouse Manor to visit her aunt, who married Dr. Storm some years ago. Once they arrive, the pair realise rather quickly that something is wrong, probably because the other guests have had their brains surgically removed, or all the blood pouring from the sink, or possibly just because the creepy midget keeps telling them to brush their teeth.
A scientist working on cures for rare afflictions, such as a bone softening agent made from molds to allow him to correct the spinal deformity of his nurse, finds the physical causes of lycanthropy in wolf-man Larry Talbot and of vampirism in Count Dracula, but himself becomes afflicted with homicidal madness while exchanging blood with Dracula.
When legendary hunter Bob Rainsford is shipwrecked on the perilous reefs surrounding a mysterious island, he finds himself the guest of the reclusive and eccentric Count Zaroff. While he is very gracious at first, Zaroff eventually forces Rainsford and two other shipwreck survivors, brother and sister Eve and Martin Towbridge, to participate in a sadistic game of cat and mouse in which they are the prey and he is the hunter.
When a woman's father goes missing, she enlists a local to aid in her search. The pair soon discover that her father has died at the hands of a wealthy sportsman who hunts homeless men as a form of recreation.
Now confined to a mental hospital, young Kirsty insists her supposedly dead father is actually stuck in Hell following his wife’s betrayal. Few believe the young woman’s lurid stories aside from the thrill-seeking Dr. Channard. Kirsty is undeterred and, with the help of a fellow patient, heads to Hell for a rescue.
A depraved scientist falls madly in love with a young woman and turns her lover into a hideous monster for meddling in his diabolical plans.
In "Multo", a young groom in Baguio for his honeymoon is possessed by a homicidal spirit when he discovers a cursed ring and decides to wear it. "Kulam" is set in the eerie halls of a mysterious hospital where a doctor practice voodoo and dead bodies go wandering in the night. "Aswang" is about a student who is a guest at a town fiesta in a remote province. The people's hospitable ways leave her clueless about a ritual that takes place at night.
After Malukan immigrants engage in a string of corpse mutilations at various New York City hospitals, a doctor and a morgue assistant travel to the Maluku Islands to investigate.
A homeless man is hired as a survival guide for a group of wealthy businessmen on a hunting trip in the mountains, unaware that they are killers who hunt humans for sport, and that he is their new prey.
University professor George Kingsley is struck by gangsters while crossing the street, leaving him with brain damage and one of the gangsters, Cannon, paralyzed. Kingsley's friend Dr. Sovac attends to both men, and when Cannon offers him a reward for aiding his recovery, Kovac transplants part of Cannon's brain into the dying Kingsley's skull, creating a dual personality.
Two couples are on a boating trip when they come across an uncharted island. The four investigate and find themselves in the clutches of Dr. Albert Balleau, whose hobby is hunting both animals and humans… The group tries to escape only to be thwarted by Dr. Balleau and his henchmen.
An ex-vaudeville actor is working as the assistant to a doctor who has Frankenstein aspirations. The ex-vaudeville actor kills the doctor and decides to assume the identity of the dead physician.
Dr. Leon Kravaal develops a potential cure for cancer, which involves freezing the patient. But an experiment goes awry when authorities believe Kravaal has killed a patient. Kravaal freezes the officials, along with himself. Years later, they are discovered and revived in hopes that Kravaal can indeed complete his cure. But human greed and weakness compound to disrupt the project.
On their way to Spring Break, college kids take a detour through an old Southern town. The people of Pleasant Valley insist the kids stay for their annual barbecue celebration... but instead of getting a taste of the old South, the old South gets a taste of them!
An unnamed doctor has always had everything he's ever wanted, but that has only made him develop more extreme and depraved needs. He kidnaps a young couple in the prime of their life together and forces them into a game of torment that slowly extinguishes their hopes for survival.
A fugitive, dangerous madman reaches an English village where he confronts his former partner who left him for dead in the jungle after their discovery of a diamond mine. When the former partner also claims to have since lost the mine and all its wealth, which he took all for himself, and though the partner is still living in a state of luxury , the madman takes up an offer from a crazed scientist to make him invisible, something the scientist has already done with experimental animals, so that he can take revenge.
In 19th century England, a noted brain surgeon rescues a former student from being hanged on a false conviction for murder, and spirits him away to an ancient, repurposed abbey far in the countryside. There, he connives his pupil into assisting him in mapping the functions of the various parts of the human brain, using living subjects who are under a terrible animation-suspending drug called "black sleep". Subsequently, the student, along with the daughter of one of the subjects, discover that most of these subjects have survived but are being kept in a dungeon-like cellar, in various stages of physical and mental derangement...
An unlucky woman’s mother is murdered by a scarf-wielding killer named Silk, leaving the woman injured, traumatised and suffering from amnesia. She’s committed to a mental institution, where Silk follows her, looking for the papers he was trying to get from her mother. And Silk’s only the beginning of her problems, since the asylum is run by a mad doctor, performing experiments in chemical lobotomies!
Dr. Bonner plans to live forever through periodic gland transplants from younger, healthier human victims. Bonner looks about 40; he's really 104 years old. But people are starting to get suspicious, and he may not make 200.