Chaney plays two roles: mad scientist Arthur Lamb and Lamb's "experiment", known only as the Ape Man. This hideous creature was the result of Lamb's attempts to transplant animal glands into human beings. A lost film.
An insane surgeon's obsession with an actress leads him to replace her wounded pianist husband's hands with the hands of a knife murderer--hands which still have the urge to throw knives.
Confined to a mental hospital, young Kirsty Cotton insists her supposedly dead father is stuck in hell, controlled by sadomasochistic demons after being betrayed by his evil, occult-obsessed wife, Julia. Few believe Kirsty, except the thrill-seeking Dr. Channard, who is intrigued by the young woman's lurid stories. So when Kirsty and fellow patient Tiffany head to hell for a rescue, Channard and Julia are close behind.
War veterans visit a lakeside cabin for a week of shooting, drinking, etc. but find the cabin being looked after by a young caretaker named David. When David's status as a war deserter is revealed, all hell breaks loose.
Professor Frankenstein creates a teenager from an accident victim, who gets angry when he learns he is going to be taken apart.
University professor George Kingsley is struck by gangsters while crossing the street, leaving him with brain damage and one of the gangsters, Cannon, paralyzed. Kingsley's friend Dr. Sovac attends to both men, and when Cannon offers him a reward for aiding his recovery, Kovac transplants part of Cannon's brain into the dying Kingsley's skull, creating a dual personality.
On their way to Spring Break, college kids take a detour through an old Southern town. The people of Pleasant Valley insist the kids stay for their annual barbecue celebration... but instead of getting a taste of the old South, the old South gets a taste of them!
After Malukan immigrants engage in a string of corpse mutilations at various New York City hospitals, a doctor and a morgue assistant travel to the Maluku Islands to investigate.
A brilliant but deranged neurosurgeon becomes obsessively fixated on a judge's daughter. With the help of an escaped criminal whose face he has surgically deformed, the mad man lures her, her father, and her fiancé to his isolated castle-like home, where he has created a torture chamber with the intent of torturing them for having 'tortured' him.
After a team of surgeons botches his beloved wife's operation, the distraught Dr. Phibes unleashes a score of Old-Testament atrocities on his enemies.
A homeless man is hired as a survival guide for a group of wealthy businessmen on a hunting trip in the mountains, unaware that they are killers who hunt humans for sport, and that he is their new prey.
The eminent Dr. Phibes awakens from a decade of suspended animation and heads to Egypt with the corpse of his dead wife, which he intends to resurrect by murdering people in strange and heinous ways.
Two couples are on a boating trip when they come across an uncharted island. The four investigate and find themselves in the clutches of Dr. Albert Balleau, whose hobby is hunting both animals and humans… The group tries to escape only to be thwarted by Dr. Balleau and his henchmen.
An ex-vaudeville actor is working as the assistant to a doctor who has Frankenstein aspirations. The ex-vaudeville actor kills the doctor and decides to assume the identity of the dead physician.
After a pawn shop robbery goes askew, two criminals take refuge at a remote farmhouse to try to let the heat die down, but find something much more menacing.
In "Multo", a young groom in Baguio for his honeymoon is possessed by a homicidal spirit when he discovers a cursed ring and decides to wear it. "Kulam" is set in the eerie halls of a mysterious hospital where a doctor practice voodoo and dead bodies go wandering in the night. "Aswang" is about a student who is a guest at a town fiesta in a remote province. The people's hospitable ways leave her clueless about a ritual that takes place at night.
When legendary hunter Bob Rainsford is shipwrecked on the perilous reefs surrounding a mysterious island, he finds himself the guest of the reclusive and eccentric Count Zaroff. While he is very gracious at first, Zaroff eventually forces Rainsford and two other shipwreck survivors, brother and sister Eve and Martin Towbridge, to participate in a sadistic game of cat and mouse in which they are the prey and he is the hunter.
When a woman's father goes missing, she enlists a local to aid in her search. The pair soon discover that her father has died at the hands of a wealthy sportsman who hunts homeless men as a form of recreation.
A mad scientist creates a monster called "Mosaico," who breaks out of the laboratory to hunt down and kill beautiful women.
An obsessed scientist conducts profane experiments in evolution, eventually establishing himself as the self-styled demigod to a race of mutated, half-human abominations.