Mail call. Nothing for Tom, but at Jerry's box, Tom finds a package; inside is a book, "Life with Tom" by Jerry Mouse. As Tom flips to chapters and hears, first a radio audience, then a group of alley cats, then Spike and Tyke, all laughing over the book, we see the clips from earlier shows that everyone is laughing at. Tom gets more and more irate about being the butt of everyone's jokes, and confronts Jerry, clobbering him with the book, when Jerry shows Tom the rest of his mail. The royalty checks have come in, and Jerry has split his $50,000 royalty with Tom. Suddenly, with $25,000 in his pocket, Tom is able to find the book funny.
Tom is all set to eat Jerry when a hawk swoops down and grabs Jerry. To get Jerry back, Tom poses as a female hawk and quickly finds his new lover to be more than he bargained for.
Tom hears a ghost story on the radio and is spooked by it; Jerry notices this and takes advantage of it, using a variety of tricks to scare Tom.
Jerry narrates in voiceover: Tom has fallen hard for the cat next door, and competes with rich cat Butch for her affections. But Butch outspends Tom to a ludicrous level at every turn. Tom goes downhill after that, until we see him contemplating suicide.
The Easter bunny brings an egg for Tom and Jerry that hatches into the little duckling. He keeps getting into water he shouldn't: the aquarium, water cooler, bathtub, sink, as the boys keep rescuing it. They try to give the duck back to the Easter bunny - no go. They leave it in the pond at the park and think they're home free, until the duckling brings his friends home.
Jerry is far from Tom's servant here. Tom, shipwrecked, washes up on a tropical island. His first attempts at food - a coconut and a turtle - are much too hard. But he spots Jerry just before Jerry sees him, and soon has him in the frying pan. Jerry escapes to a cannibal village; when he sees Tom's frightened reaction, he has his plan. Using soot from a pot, he blackens himself, then threatens Tom and starts cooking him. But Jerry's plan - and tail, and un-blackened bottom - is exposed when his grass skirt comes off during his war dance. Jerry helicopters away using the bone in his hair, and leading Tom right into the real cannibals. But Jerry's triumph is short-lived, as a pygmy cannibal comes after him.
Tom subjects Jerry to his usual harassment; but the cat finds a new enemy, and the mouse finds a new friend, in the canary of the house.
Mammy Two-Shoes replaces Tom with a younger cat who is a lightning-quick mouser. Tom and Jerry form an alliance in order to get rid of this dangerous newcomer.
Tom is given the task of guarding the fridge during the night by Mammy-Two-Shoes, but as soon as he has started he is tricked by Jerry into falling into the basement, where he lands in a barrel of cider. Now drunk, Tom staggers around in the house getting up to no good with Jerry.
Jasper is given an ultimatum by his master: break one more thing and you're out. Rodent Jerry does his best to make sure that his tormentor "gets the boot".
Jerry is awakened from a nightmare by a knock on the door: someone has left a foundling in a walnut shell with a note, giving his name as Nibbles and saying he needs lots of milk. Fortunately, there's a dish handy, but it's next to Tom. Nibbles scurries out and dives off Tom's nose, then grabs a whisker for balance, waking Tom up. Jerry grabs him just in time and they hide under the milk. Tom laps up some milk and gets Nibbles; Jerry rescues him, and they run for the hole. Next, they try a very long straw; Tom catches them and sucks Nibbles through the straw. Much chasing follows, with a pause now and then for some milk. Tom traps Jerry in a milk bottle and chases Nibbles a while; he finally corners Nibbles and spanks him with a flyswatter. Jerry is so enraged he burst out of the milk bottle and lets out a ferocious roar; he grabs Tom by the tail and thoroughly pummels him, then stands over him as Tom feeds Nibbles milk.
Mammy Two-Shoes threatens to throw Tom out of the house if he makes a mess. Jerry sees an opportunity to rid himself of his feline nemesis.
Tom's day at the beach doesn't start out well. First he gets his swimsuit caught in the door of the beach house, and doesn't realize it until his intended dive in the ocean sends him snapping back and crashing through the door. He runs out and tries again. This time he is so determined to jump in the water that when he does so, he doesn't notice the tide is out and that he is swimming in the sand, which is filled with broken bottles, tin cans and other debris. Later, he tries to win over a beautiful girl on the beach, but, being the boor he is, he annoys her by drinking her soda pop, eating her hot dog and munching loudly as he lays his head in her lap. Suddenly, a tomato flies through the air and lands on his head. So does a banana peel. Tom looks for the culprit and finds him in the girl's picnic basket. Jerry is inside, eating what he wants and tossing out the rest...
Tom and Jerry are in a bowling alley. Both spend a lot of time sliding on the well-polished lanes. Eventually, Jerry takes up residence among the pins and Tom tries to bowl him down.
Mammy Two-Shoes tells Tom and Butch that the cat who gets rid of the icebox-raiding, breadbox-invading mouse (Jerry) is the one who can stay.
Tom's new book on "how to catch a mouse" doesn't prove too helpful against Jerry; actually, Jerry seems to make better use of it than Tom.
Tom is playing with Jerry when a cute lady cat is delivered to Mammy for her to take care of. Tom is smitten at first sight.
The family dog warns Tom not to make any noise so he can take a nap. Jerry hears this and immediately devises plans to ensure that the dog's nap will be interrupted.
It's spring, and Tom is much more interested in the female cat next door than in Jerry.
Tom fights with another cat over Jerry.