A pair of weed-loving, free lance video journalists find themselves targeted by a mark they slandered in one of their exposes.
David is an artist and a pothead. He's fallen in love with the beautiful and sexy Serena, and things are going simply splendidly until poor David's house burns down. Serena doesn't need the bad vibes, so she splits the scene and runs off to New York with rocker and junkie Tommy. Lonely David finally turns to the sweet, sweet comfort of marijuana and his strange menagerie of friends to forget about his lost home and love
Over the course of three days Ross, a college dropout addicted to crystal-meth, encounters a variety of oddball folks - including a stripper named Nikki and her boyfriend, the local meth producer, The Cook - but all he really wants to do is hook up with his old girlfriend, Amy.
Seven old college friends gather for a weekend reunion after the funeral of one of their own.
It is 1967, and Larry Gopnik, a physics professor at a quiet Midwestern university, has just been informed by his wife Judith that she is leaving him. She has fallen in love with one of his more pompous acquaintances Sy Ableman.
From an ominous Lecturer, a small 1930s middle American community learns of the Harper Affair, in which young Jimmy Harper finds his life of promise turn into a life of debauchery and murder thanks to the new drug menace marijuana. Along the way, he receives help from his girlfriend Mary and Jesus Himself, but always finds himself in the arms of the Reefer Man and the rest of the denizens of the Reefer Den.
Alex, Emily, and their son, RJ, are new to Los Angeles. A chance meeting at the park introduces them to the mysterious Kurt, Charlotte, and Max. A family “playdate” becomes increasingly interesting as the night goes on.
Party girls Kirsten, Jade and Heather are heading out for a night of pot and booze when they are carjacked by a crazed woman holding a bag of stolen money. The woman rants about being on the run from vampires and then holds the girls hostage in their home. The girls bide their time and don't believe the woman's nutty story...until a creepy stranger shows up at their window.
A white dropout struggles to become a cartoonist and filmmaker, drawing inspiration from the harsh, gritty world around him. Still sharing his rundown apartment with his middle-aged parents, an oafish slob of an Italian father and a ditzy nutcase of a Jewish mother, he's ridiculed and looked down upon by his friends, hypocrites who run with violent gangs and the Italian Mafia, and a shallow Black girl who makes her living downtown with the pimps and pushers. The cartoonist gets a chance to pitch a film idea to a movie mogul, but the story proves too outrageous: a far-future Earth, depleted by war and pollution, where a mutant antihero challenges and kills God.
Ben Singer is a failed children's folk singer, a career proofreader, a less-than-extraordinary weekend dad, and perhaps the most negative man alive. Floundering in all aspects of his life, Ben's only comfort comes from regular chess games and friendly debates on game theory with his Senegalese roommate Ibou. When Ibou is suddenly struck ill, Ben's pessimistic worldview seems unequivocally confirmed. It takes an extended visit from Ibou's sister Khadi for Ben to realize that cynicism may be all a matter of perspective.
Ricky, Julian and Bubbles are about to get out of jail, and this time, Julian vows to go straight, even open a legit business. Soon the Boys will all be rich. At least that's what they've told the parole board. But when they arrive back at the park, they find it's not the same old Sunnyvale - and it's not the same old Jim Lahey, Trailer Park Supervisor.
Jean-Claude is a loud-mouthed, know-it-all and full time boor who is best friends with Stef, a self-styled lady killer who would do better with the fairer sex if he could work up the ambition to wake up in the morning. Stef has decided that he may need some help in finding the woman of his dreams, and embracing loyalty rather than logic he turns to Jean-Claude for advice.
Two middle-aged men embark on a spiritual journey through Californian wine country. One is an unpublished novelist suffering from depression, and the other is only days away from walking down the aisle.
A former Los Angeles drug dealer moves far away to Texas, making a new life for himself as a married architect in the suburbs. His old crime partner unexpectedly shows up with heroin and gangster business, attracting a slew of violent unsavory characters.
Even though he's 35, Alex acts more like he's 13, spending his days as the world's oldest video game tester and his evenings developing the next big Xbox game. But when he gets kicked out of his apartment, he's forced to move in with his grandmother.
The boys get arrested for robbing an ATM machine and spend 18 months in jail, upon release they decide to pull off "The Big Dirty", a plan to steal a large amount of coins because they are untraceable and quit their life of crime forever.
Kyle Fisher has one last night to celebrate life as a single man before marrying Laura, so he sets out to Vegas with four of his best buddies. But a drug and alcohol filled night on the town with a stripper who goes all the way, turns into a cold night in the desert with shovels when the stripper goes all the way into a body bag after dying in their bathroom. And that's just the first of the bodies to pile up before Kyle can walk down the aisle...
Jack comes to Amsterdam to find his father and, through a momentary magical encounter, finds the secret weapon that could turn around his father's ailing marijuana coffee shop.
After her husband runs off with his secretary, Terry Wolfmeyer is left to fend for herself -- and her four daughters. As she hits rock bottom, Terry finds a friend and drinking buddy in next-door neighbor Denny, a former baseball player. As the two grow closer, and her daughters increasingly rely on Denny, Terry starts to have reservations about where their relationship is headed.
An unemployed pot-smoking slacker and amateur drummer, Anthony Stoner ditches his strict parents and hits the road, eventually meeting kindred spirit Pedro de Pacas. While the drug-ingesting duo is soon arrested for possession of marijuana, Anthony and Pedro get released on a technicality, allowing them to continue their many misadventures and ultimately compete in a rock band contest, where they perform the raucous tune "Earache My Eye."