The Northwest Mounties are after Cheyenne Harry for the murder of an Indian boy, and the only witness to the crime is a priest - who can't tell what he saw because the real killer, Black Michael, has confessed to him.
Secret Serviceman Allen takes a job at Bart Stevens' mine in order to find evidence proving that Stevens is a mail robber named Smoke Gublen. He does - but by then, he is in love with the man's sister - and to make things harder, Stevens saves his life...
Rustler Pete Sontag kidnaps Merlin Warner after he kills her father. Pete, a drug smuggler who uses his saloon as a front, coerces Merlin though beatings to become the dancer Mexicali Mae. She meets and falls in love with morphine addict Joe Blanchard but Pete frames Joe for a murder that he committed, forcing Mae to hide Joe in a homestead in the hills. After many struggles, Joe is cured of his addiction and proposes to Mae. She accepts, but when his mother and fiancée Eleanor arrive, they offer her money to leave, Mae refuses the money but becomes convinced that she is not good enough for Joe and writes to him that she is returning to the saloon. Joe learning of his mother’s plot arrives at the saloon and in the resultant fight Pete is killed. Mae and Joe are reconciled.
Returning to his father's cattle ranch after the excitement of serving in combat overseas, Bud McGraw becomes restless, and his father decides to send him to an old friend who commands the Border Police in Texas. On the way he meets Peggy Hughes, accompanying her Uncle Graham, a customs inspector, and he retrieves her hat from the rails of a train. At the headquarters, numerous scrapes and fights win him the admiration of, and friendship with, the men. Lazaro, a Secret Service agent, invites Mrs. Graham and Peggy, who are staying at the border station, for an automobile ride, and they are captured by bandits and held for ransom. Bud and his pals deliver the ransom and discover that Lazaro is the bandit chief. Lazaro refuses to release Peggy, but a jealous rival, Nita de Garma, causes his downfall and shoots him as the Border Police arrive to rescue the party.
Jim Blake, the playboy son of a New York millionaire, heads west to prove himself a man. He goes to work on his father's ranch in Wyoming, and eventually wins over the locals by turning the tables on a town bully and trying to collect damages from a railroad magnate, whose trains have killed many of the Blake ranch's cattle. When the railroad refuses to pay, Jim comes up with a plan that will make them pay far more than they originally had to. Problems arise when he falls in love with Alice, the railroad magnate's daughter.
Moran, blind to ambition, has been a long-time friend of the widow Casey. In his own way Moran likes the widow, but his strongest affection is for her young son. The boy, in turn, loves the man's friendship and the knife the man has given him. The time comes when the widow and Moran fight.
Discouraged by the loss of his job and unable to find another young shipping clerk Clark heads west, promising his mother that he will send for her when he finds a decent job. Instead, he falls into bad company. Finding it hard to make money he first works in prospecting without success until finally securing a job in a mine.
Mining foreman Jimson is fired by Pedro and Madro when they falsely accuse him of trying to steal ore. When they attack him, he is forced to strike back, and they swear revenge. Their enmity intensifies when Jimson rescues Nina, a Mexican girl, from Pedro's unwanted attentions.
Deputy Sheriff Martin of Arizona is in love with Lola a waitress at the Gold Dollar restaurant. However, complications arise when Martin encounters James Kinney, a wanted murderer working under an assumed name in the local mine. Deputy Martin discovers that Kinney is also interested in Lola, fueling a rivalry between the two men. During a mine accident, Kinney is placed in a dangerous situation and Martin must decide whether to act on his personal feelings or uphold his duty as a lawman.
Jeremy Dexter, Sheriff of Sherman County, warns Lanky Mason to leave town after being involved in a shootout the night before killing a Mexican. The sheriff tells Lanky that although he remembers that Lanky had saved his little daughter's life by swimming across a stream during a flood and that Lanky's heroic work during a time when the smelter caught fire had saved the town from destruction, it was imperative for the good of the town that Lanky leave.
The sheriff loses his office and a new sheriff comes in. Now the ex-sheriff is going bad, drinking, etc., with no ambition. The tough guys take advantage of his loss of ambition and indignities pile up on him and he makes no protest. He meets the new sheriff's little boy and they become fast friends.
Jerry Kane, a man down on his luck who inherits money but selflessly gives most of it to Maizie Wallace and her sick father. The money is then stolen by two crooks, Pinny Falk and Big Dan Jaffry, leading to a series of events involving a pursuit, mistaken identity, a fight, and a rescue by a posse. Ultimately, the crooks are captured, the money is recovered, and Jerry and Maizie agree to share their future together.
Miner Jim Mann is indifferent to the new baby and sees him as nothing more than an additional burden. His wife Lucy looks after the baby and is unable to help much with the work, and Jim's dinner is often late. He grows to dislike the child and refuses to hold or pet him. Dawson, another miner, and his wife and their small baby occupy the cabin on the adjacent claim.
Miner Holton lives and works with his daughter Leota near Stormy Creek. Leota loves Dick Raleigh, though her father objects. When prospector Tom Andrews is injured near their home Leota and Dad nurse him back to health and give him work in their little mine. In repayment he intends to steal from them taking advantage when Holton is hurt while Leota is away but Dick thwarts him and he and Leota are united with her father’s blessing.
Miner John Walsh leaves his wife and baby behind on his barren claim taking their small store of gold to the settlement and gambling it away. He becomes embroiled in a fight with cowpuncher Burns and is killed. Shortly afterwards Mrs. Walsh, weakened by her attempt to work, her husband's claim collapses. The doctor declares only a transfusion can save Mrs. Walsh's life. Burns, now a fugitive, appears and volunteers. Mrs. Walsh's life is saved, but Burns, weakened by hunger and exposure, succumbs, happy in having made amends for his crime.
On the rim of the desert The Brute runs a saloon with an iron hand which he also uses on The Woman. When The Man wanders in and wins at poker The Brute tries to fleece him of his winnings but loses everything when suddenly The Man catches sight of The Woman. He offers to stake his all on her and they play. The Man has four of a kind. The Brute has a gun. But The Man is a quicker draw and the pair escape across the desert. The Brute follows but when he is defeated in a showdown he wanders off into the desert to perish. The Man and The Woman embark on a new life.
In this Western, Frank Keenan has a dual role -- kind-hearted gambler John Lynch and evil bandit Big Rivers. The only person who realizes there is a resemblance between the two is dance hall girl Nita (Maude George), who was abused by the outlaw and cared for by Lynch.
In the Old West Charles Garvin and Clarice Winslow are happily engaged. One day artist, Ed Gardner arrives seeking lodging and is welcomed into Clarice's home, where he meets the young cowboy. However, when Charles must depart for a round-up, Ed begins to charm Clarice, who seems amused by his company and a triangle develops.
Johnson, a pharmacist, makes an illicit traffic in cocaine and morphine, which he cleverly sells through his drug counter to a select clientele. In his richly furnished office, the head of the Kurson Chemical Company counts the receipts of Kurson Consumption Cure, a patented drug that contains a large amount of morphine.
After years of scientific research Thomas Kellner, an eccentric chemist, succeeds in manufacturing an imitation diamond, with the help of his son Jack.