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A high-school track star (Nick Stahl) watches without judgment as his two best friends (Summer Phoenix, Aaron Paul) abuse heroin.

Juggling increasing career success and a growing heroin habit, a television comedy writer attempts to go down a path of improvement.

Saxophone player Charlie ‘Bird’ Parker comes to New York in 1940 and is quickly noticed for his remarkable way of playing. He becomes a drug addict but his loving wife Chan tries to help him.

Undercover cop Jim Raynor (Jason Patric) is a seasoned veteran. His partner, Kristen Cates (Jennifer Jason Leigh), is lacking in experience, but he thinks she's tough enough to work his next case with him: a deep cover assignment to bring down the notoriously hard-to-capture drug lord Gaines (Gregg Allman). While their relationship turns romantic during the assignment, they also turn into junkies, and will have to battle their own addictions if they want to bring down Gaines once and for all.

The family of Raymond, his wife Val and her brother Billy live in working-class London district. Also in their family is Val and Billy's mother Janet and grandmother Kath. Billy is a drug addict and Raymond kicks him out of the house, making him live on his own. Raymond is generally a rough and even violent person, and that leads to problems in the life of the family.

A waitress confronts all the wrong turns she has made in her short life and ultimately ends up facing the biggest wrong turn of all: her dangerous ex-boyfriend who's determined to win back her love or die trying.

Bill is targeted by pot pushers who use him as their entry to the "good kids." Needing money because his mother is sick and his father is absent, he drops out of school to become a pusher. He seeks help after seeing his supplier shoot up.

London police and reporters from a local newspaper go after a gang of foreign criminals.

In underworld terms, Chas Devlin is a 'performer,' a gangster with a talent for violence and intimidation. Turner is a reclusive rock superstar. When Chas and Turner meet, their worlds collide—and the impact is both exotic and explosive.

Zed is an American vault-cracker who travels to Paris to meet up with his old friend Eric. Eric and his gang have planned to raid the only bank in the city which is open on Bastille day. After offering his services, Zed soon finds himself trapped in a situation beyond his control when heroin abuse, poor planning and a call-girl named Zoe all conspire to turn the robbery into a very bloody siege.

This movie portrays the drug scene in Berlin in the 70s, following tape recordings of Christiane F. 14 years old Christiane lives with her mother and little sister in a typical multi-storey apartment building in Berlin. She's fascinated by the 'Sound', a new disco with most modern equipment. Although she's legally too young, she asks a friend to take her. There she meets Detlef, who's in a clique where everybody's on drugs. Step by step she gets drawn deeper into the scene.

Set in the Little Saigon district outside of Sydney, a woman trying to escape her past becomes embroiled in a drug deal.

A microcosm of people lost in search of an artificial happiness, which leads them to steal and prostitute themselves for the short ecstasy of a squirt of heroin in the veins. Marco and Pina live in this world of drugs, prostitution and violence, and they must fight for their survival. One day one of their friend dies during a holdup. Marco and Pina are helpless and will do anything to escape, but fate does not want a similar world. Between bites of heroin and sidewalk they are in a deadly trance.

A criminal subculture operates among U.S. soldiers stationed in West Germany just before the fall of the Berlin wall.

Following the death of his employer and mentor, Bumpy Johnson, Frank Lucas establishes himself as the number one importer of heroin in the Harlem district of Manhattan. He does so by buying heroin directly from the source in South East Asia and he comes up with a unique way of importing the drugs into the United States. Partly based on a true story.

While investigating a young nun's rape, a corrupt New York City police detective, with a serious drug and gambling addiction, tries to change his ways and find forgiveness.

A young boy trying to deal with his mother's heroin addiction befriends a waitress who helps him cope with the tough situation.

After finally breaking up with his drug-addicted lover, Trevor begins a new romance that unexpectedly complicates his other relationships.

The drug-induced utopias of four Coney Island residents are shattered when their addictions run deep.

Determined to have a normal family life once his mother gets out of prison, a Scottish teenager from a tough background sets out to raise the money for a home.