Baggage handlers Bud and Lou accidentally stumble upon Frankenstein's Monster, Dracula and the Wolf Man.
Frankenstein's unscrupulous colleague, Dr. Bohmer, plans to transplant Ygor's brain so he can rule the world using the monster's body, but the plan goes sour when he turns malevolent and goes on a rampage.
Blackmailing a young couple to assist with his horrific experiments the Baron, desperate for vital medical data, abducts a man from an insane asylum. On route the abductee dies and the Baron and his assistant transplant his brain into a corpse. The creature is tormented by a trapped soul in an alien shell and, after a visit to his wife who violently rejects his monstrous form, the creature wreaks his revenge on the perpetrator of his misery: Baron Frankenstein.
Baron Victor Frankenstein has discovered life's secret and unleashed a blood-curdling chain of events resulting from his creation: a cursed creature with a horrid face — and a tendency to kill.
Dr Simon Helder, sentenced to an insane asylum for crimes against humanity, recognises its director as the brilliant Baron Frankenstein, the man whose work he had been trying to emulate before his imprisonment. Frankenstein utilises Helder's medical knowledge for a project he has been working on for some time. He is assembling a man from vital organs extracted from various inmates in the asylum. And the Baron will resort to murder to acquire the perfect specimens for his most ambitious project ever.
Rescued from the guillotine by his devoted dwarf Fritz, the Baron relocates to Carlsbruck, where he continues his gruesome experiments.
A student receives a serial killer's brain in a transplant after being thrown into a pool with no water in it.
University professor George Kingsley is struck by gangsters while crossing the street, leaving him with brain damage and one of the gangsters, Cannon, paralyzed. Kingsley's friend Dr. Sovac attends to both men, and when Cannon offers him a reward for aiding his recovery, Kovac transplants part of Cannon's brain into the dying Kingsley's skull, creating a dual personality.
Journalist Mike Harway decides to help his friend Christine in her search for her father, professor Baker, who mysteriously disappeared. The investigation brings them to Africa where they are captured and brought to the El Faium abandoned fort. It now hosts a laboratory designed by the twisted mind of Devilman, who dreams of swapping his natural brain with an artificial one that will make him perfect.
A rich but unscrupulous old woman plots with a scientist to have her brain implanted in the skull of a sexy young woman.
A strikingly beautiful and wealthy woman is hit by a truck and is all smashed up and nearly killed. At nearly the same time, a very plain looking lower middle class woman simply faints and suffers brain death. The beautiful womans brain is fine, so, doctors merely transplant her brain into plain Jane. Problems ensue when plain Janes husband continues to believe she is still his wife. She has no memory of him, and goes to live with the beautiful womans husband. She doesn't mix well with her new socialite friends and family. Mirrors are emotional battlefields as well.
Brought back to life by an unorthodox scientist, a young woman runs off with a lawyer on a whirlwind adventure across the continents. Free from the prejudices of her times, she grows steadfast in her purpose to stand for equality and liberation.
The discovery of a perfectly preserved caveman prompts a mad scientist to attempt a daring brain transplant.
Amir, the benevolent ruler of Kalid, is dying, but there is hope. Freshly deceased, he is flown to the United States where Dr. Trenton transplants his brain into the body of a simpleton in a classic "assistant got the wrong kind of body" plot line. Dr. Trenton has a few nefarious plot twists of his own in mind, and then there's the thing with the dwarf and the women chained in the basement. It's up to Amir's friend Bob and wife Tracey to try and salvage this tale.
A brilliant surgeon encases his dead son's brain in a large robot body, with unintended results...
An evil scientist implants the brain of a murdered high school student into an animatronic Tyrannosaurus, who later wreaks vengeance on the bullies who killed him, and is reunited with his sweetheart.
Once again Paula the ape woman is brought back to life, this time by a mad doctor and his disfigured assistant, who also kidnaps a nurse in order to have a female blood donor.
After a traffic accident Kaylie is in coma for months and her doctors want to try a new procedure on her. To regain her consciousness, they stimulate her brain with the neural patterns of a woman who has just died. It works and Kaylie fully recovers. However, she begins to relive the dying moments of her donor and realizes that she was murdered! Along with her husband and mother, she tries to find out what happened.
A mad scientist terrorizes a city by kidnapping young women with his ape-man Gomar and then using them as subjects in sadistic brain transplant experiments. A female wrestler whose sister was one of the victims swears vengeance against the Mad Doctor.
A white man's brain is transplanted into a black man's skull.