Eight years after seemingly destroying the killer doll, teen Andy Barclay is placed in a military school, and the spirit of Chucky returns to renew his quest and seek vengeance after being recreated from a mass of melted plastic.
When a serial killer interrupts the fun at the swanky Coconut Pete's Coconut Beach Resort -- a hedonistic island paradise for swingers --- it's up to the club's staff to stop the violence ... or at least hide it!
Following the arrest of her mother, Ramona, young Vanessa Lutz decides to go in search of her estranged grandmother. On the way, she is given a ride by school counselor Bob Wolverton. During the journey, Lutz begins to realize that Bob is the notorious I-5 Killer and manages to escape by shooting him several times. Wounded but still very much alive, Bob pursues Lutz across the state in this modern retelling of Little Red Riding Hood.
FBI agent Joel Campbell, burnt-out and shell-shocked after years spent chasing serial killers, flees L.A. to begin a new life for himself in Chicago. But five months later, Joel's best laid plans are abruptly cut short when his new hometown becomes the setting for some particularly gruesome murders--murders that could only have been committed by one man: David Allen Griffin. One of Joel's most elusive and cunning nemeses, Griffin has followed his former pursuer to Chicago in order to play a sadistic game of cat and mouse. Taunting Joel with photographs of his intended victims and leaving his crime scenes meticulously free of clues in order to keep the police at bay, Griffin derives as much pleasure out of watching Joel react to every movement as watching his victims die. But when Griffin moves into Joel's inner circle, Joel must quickly find some way to stop him before someone close to him becomes the next one to die.
Arriving in Chicago, Henry moves in with ex-con acquaintance Otis and starts schooling him in the ways of the serial killer.
Rachel is a criminology student hoping to land a position as a teacher's assistant for professor Robert Starkman. She's sure this position will pave the way to an FBI career, and she's willing to do anything to obtain it -- including killing her classmates. The school psychiatrist, Dr. Daniels, becomes aware that Rachel is insane, but Rachel is skilled at her dangerous game of death and identity theft.
Jess Koster is a young attorney in LA who is being stalked by the serial killer she is prosecuting.
Trapped inside a fortified home owned by a mysterious couple, a young boy quickly learns the true nature of the homicidal inhabitants, and secret creatures hidden deep within the walls.
Clarice Starling is a top student at the FBI's training academy. Jack Crawford wants Clarice to interview Dr. Hannibal Lecter, a brilliant psychiatrist who is also a violent psychopath, serving life behind bars for various acts of murder and cannibalism. Crawford believes that Lecter may have insight into a case and that Starling, as an attractive young woman, may be just the bait to draw him out.
After FBI agent Frank Lacrosse believes his son was kidnapped by a notorious serial killer, he travels to Amarillo, Texas, where he believes the murderer is in hiding. Although officially taken off the case because of its personal significance to him, Frank continues to pursue the killer, causing concern for local sheriff Buck Olmstead. When another victim pops up at a nearby car garage, Frank knows that he is as close as he'll ever be to tracking down the elusive killer.
A journalist duo go on a tour of serial killer murder sites with two companions, unaware that one of them is a serial killer himself.
The next great psycho horror slasher has given a documentary crew exclusive access to his life as he plans his reign of terror over the sleepy town of Glen Echo, all the while deconstructing the conventions and archetypes of the horror genre for them.
When a prominent art dealer is found murdered, the man's death leads to an intriguing investigation steeped in sex, corruption and crime. District Attorney David Corelli gets assigned to the case and discovers that a key suspect is his ex-lover Katrina Gavin, a beautiful psychologist who has settled down with his old friend and peer. As Corelli gets deeper into the case, he uncovers dark secrets with far-reaching implications.
Four friends start to receive morbid Valentine cards and realise they are being stalked by someone they had spurned 13 years ago. A masked killer is on the loose and Valentine's day is soon approaching.
Coming from a police family, Tom Hardy ends up fighting his uncle after the murder of his father. Tom believes the killer is another cop, and goes on the record with his allegations. Demoted to water-way duty Tom, along with new partner Jo Christman, navigate the three rivers looking for clues and discovering bodies. This time the victims are women Tom knows, he must find the killer to prove his innocence.
The ambitious young Ina Littmann is an investigative journalist for the TV talk show "Eye in Eye". Her current subject is Henry Kupfer, who wrote a bestseller about a psychopathic killer after he was himself in prison for 8 years for manslaughter. As an entry for the show Ina plans to use a current series of brutal murders among prostitutes. When Ina meets Kupfer, she is despised and fascinated at the same time. Soon she's convinced that Kupfer not only writes about murders, but commits them himself. She smells a smash hit and prepares to prove him guilty on the show.
A mysterious man arrives at the offices of an FBI agent and recounts his childhood: how his religious fanatic father received visions telling him to kill people who were in fact "demons."
Chris Miller, living with her stepmother in a large secluded mansion, finds her isolation interrupted by the arrival of an unknown scythe-wielding killer.
When secretive new neighbors move in next door, suburbanite Ray Peterson and his friends let their paranoia get the best of them as they start to suspect the newcomers of evildoings and commence an investigation. But it's hardly how Ray, who much prefers drinking beer, reading his newspaper and watching a ball game on the tube expected to spend his vacation.
Following Jigsaw's grisly demise, Detective Mark Hoffman is commended as a hero, but Agent Strahm is suspicious, and delves into Hoffman's past. Meanwhile, another group of people are put through a series of gruesome tests.