Following the Civil War, headstrong rancher Thomas Dunson decides to lead a perilous cattle drive from Texas to Missouri. During the exhausting journey, his persistence becomes tyrannical in the eyes of Matthew Garth, his adopted son and protégé.
Retired wealthy sea captain Jim McKay arrives in the Old West, where he becomes embroiled in a feud between his future father-in-law, Major Terrill, and the rough and lawless Hannasseys over a valuable patch of land.
Eddie Dean is a Cattlemen's Association agent investigating a serious rash of rustlings along with sidekicks Soapy (Roscoe Ates) and Waco (Lee Bennett. The latter bears a striking resemblance to Lawrence ranch foreman Bert Ford (also Bennett), who has been the target of several assassination attempts. Rancher Lawrence (Lee Roberts) and Eddie decide that Waco shall impersonate Ford, who is hiding out in a hotel room.
A former gunslinger is forced to take up arms again when he and his cattle crew are threatened by a corrupt lawman.
When his cattlemen abandon him for the gold fields, rancher Wil Andersen is forced to take on a collection of young boys as his cowboys in order to get his herd to market in time to avoid financial disaster. The boys learn to do a man's job under Andersen's tutelage, however, neither he nor the boys know that a gang of cattle thieves is stalking them.
One man wants to control all the land in the state to graze all his cattle. His band of outlaws are raiding ranchers and homesteaders, trying to drive them out. Rocky and Fuzzy are brought in to help stop the raiders and keep the land for the small ranchers and homesteaders.
A town is cleared of crime when a group of cowboys under the direction of Hayden battles an outlaw gang. They also manage to restore the reputation of a friend wrongly accused of murder.
A New Mexico cattle man and his strong-willed daughter clash over land and love.
Dare Rudd takes a shine to his cattleman cousin Tom's girlfriend who asks Tom to hire Dare to head the big cattle drive. Dare loses the money for the drive to cardsharps, but Tom wins it back, but Dare must save Tom's life.
Captain Porter's scheme is to buy livestock and then have his men show up later to kill the buyer and retrieve the money. When his men kill the next victim, he frames the Arizonian for the murder. The Arizonian escapes the law and joins up with the outlaw Vasquez. Knowing Porter's scheme, he plans to trap him by using Vasquez as the next buyer.
Cattle baron John Chisum joins forces with Billy the Kid and Pat Garrett to fight the Lincoln County Land War in the New Mexico Territory of 1878.
Hopalong Cassidy, boss of the Bar 20 ranch in Texas, rides down the Camino Real in the New Mexico cattle country near Alamogordo, in response to an urgent message from his lifelong sweetheart, Nora Blake, who is in serious trouble. Before he and his saddlemates, "Lucky" Jenkins and "Pappy", can reach her ranch, they are stopped by Clay Allison, a cattle-rustler who is in almost complete control of the district, and wants to extend his holdings by seizing Nora's cattle and driving her out. Seeing Cassidy as a menace to his plans, he has him arrested on a trumped-up charge. Cassidy and his pals shoot their way out of the trouble and reach Nora;s ranch where they learn that Allison's henchmen have murdered her foreman, Tom Dillon, and Allison has sent for a crew of outlaws on the Texas border.
The local school is causing Hoppy problems. First Bar 20 cattle are stolen when Hoppy investigates a problem there. Then the new teacher arrives and disrupts the routine of the Bar 20 hands. Later with the Bar 20 hands at graduation, the rustlers are poised to strike again. But there is dissension among them and this will lead to the break that Hoppy needs.
Disguising himself as a milquetoast Easterner who writes Western novels, Hoppy enrolls in a dude ranch in order to unmask the murderer of the owner's husband.
Mortimer builds a fence for the cattle brought by Ken Morley. To retaliate, Slater who wants access to the land, builds a dam cutting off Mortimer's water supply. When Ken confronts Slater, he is captured. Then lightning destroys the dam and Ken, imprisoned in a shack, is in the path of the oncoming water.
A drought is about to end the cattle business. The owner of a canning factory wants to buy all the remaining cattle cheap. He plans to ruin the cattlemen's plans to ship water by train and to seed the clouds for rain. Roy is sent by a packing house to investigate.
A young woman inherits her father's large Texas ranch and plans to begin a cattle drive to Abilene, Kansas, 1000 miles away. The crooked State Treasurer plans to attack the cattle drive and steal all of the stock so he can gain control of her ranch.
Lambert, a young man out to make his fortune, is out west trying to sell a gadget that can peel potatoes, open cans, pull out nails and perform other handy tasks. He comes to a cattle ranch and runs into a group of cowboys eating supper. He impresses the cowboys so much that they make him their leader, and it's not long before he's hired by pretty young ranch manager Vesta Philbrook as her aide and bodyguard. "The Duke", as he's now called, falls in love with her and sets out to help her get rid of a gang of vicious cattle rustlers that are constantly raiding her ranch.
Broke and in debt, an otherwise honest cowboy and his buddy get mixed up in some shady dealings with a crooked cattle dealer.
Working as an assistant on a long cattle drive, the young Ben Mockridge contends between his dream of being a cowboy and the harsh truth of the Old West.