Monette, a recently separated travelling book salesman tells his grim story to both a priest and a hitchhiker, looking for absolution.
After FBI agent Frank Lacrosse believes his son was kidnapped by a notorious serial killer, he travels to Amarillo, Texas, where he believes the murderer is in hiding. Although officially taken off the case because of its personal significance to him, Frank continues to pursue the killer, causing concern for local sheriff Buck Olmstead. When another victim pops up at a nearby car garage, Frank knows that he is as close as he'll ever be to tracking down the elusive killer.
Following the arrest of her mother, Ramona, young Vanessa Lutz decides to go in search of her estranged grandmother. On the way, she is given a ride by school counselor Bob Wolverton. During the journey, Lutz begins to realize that Bob is the notorious I-5 Killer and manages to escape by shooting him several times. Wounded but still very much alive, Bob pursues Lutz across the state in this modern retelling of Little Red Riding Hood.
Its the summer of 1974. Four friends have planned a recreational weekend hiking and camping in the forest. At a remote truck stop they pick up an anxious hitchhiker who only after a short ride demands they stop the vehicle. She is clearly frightened of somethingbut what she cant begin to describe in her carsick terror. Suddenly the group are ambushed and left unconscious.
A farm boy reluctantly becomes a member of the undead when a girl he meets turns out to be part of a band of vampires who roam the highways in stolen cars.
A young man is in a race against time as he searches for a cure after becoming infected with a virus that will eventually turn him into a blood-sucking vampire.
While driving through the New Mexico Desert during a rainy night, the college students Jim Halsey and his girlfriend Grace Andrews give a ride to the hitchhiker John Ryder. While in their car, the stranger proves to be a psychopath threatening the young couple with a knife, but Jim succeeds to throw him out of the car on the road. On the next morning, the young couple sees John in another car.
A woman on the run from her abusive husband encounters a mysterious hitch-hiker.
The rotting Creep himself is back with three new gruesome tales of horror that will make your skin crawl; a cigar store wooden Indian comes to life to avenge the store owner's brutal murder at the hands of three punks in "Old Chief Wood'nhead." The chills continue with "The Hitchhiker," The chilling tale of a woman who keeps running into, and over, the same mutilated man on a lonely road.
On their way to an afternoon on the lake, husband and wife Andrzej and Krystyna nearly run over a young hitchhiker. Inviting the young man onto the boat with them, Andrzej begins to subtly torment him; the hitchhiker responds by making overtures toward Krystyna. When the hitchhiker is accidentally knocked overboard, the husband's panic results in unexpected consequences.
Whilst on a short weekend getaway, Louise shoots a man who had tried to rape Thelma. Due to the incriminating circumstances, they make a run for it and thus a cross country chase ensues for the two fugitives. Along the way, both women rediscover the strength of their friendship and surprising aspects of their personalities and self-strengths in the trying times.
After she leaves her cheating husband, Susan Reed embarks on a cross-country road trip where she falls victim to a series of mishaps that land her behind bars in the redneck Macon County Jail. Once inside, she's subjected to endless acts of brutality from the guards and inmates alike. Things go from bad to worse when she's forced to defend herself against a rapist with tragic results. No longer truly "innocent," when the opportunity arises Susan flees with fellow prisoner Coley.
After picking up a traumatized young hitchhiker, five friends find themselves stalked and hunted by a chainsaw-wielding killer and his family of equally psychopathic killers.
On a stormy night, young Jim, who transports a luxury car from Chicago to California to deliver it to its owner, feeling tired and sleepy, picks up a mysterious hitchhiker, who has appeared out of nowhere, thinking that a good conversation will help him not to fall asleep. He will have enough time to deeply regret such an unmeditated decision.
The life of Al Roberts, a pianist in a New York nightclub, turns into a nightmare when he decides to hitchhike to Los Angeles to visit his girlfriend.
A sadistic serial killer terrorizes a couple driving on a rural highway in Texas while killing numerous people and framing them for his killings.
When a helpful family invites two lost couples in for a good ol' down-home massacre, the prom night teens find themselves all dressed up... with no place to escape.
One evening, Hammer gives a ride to Christina, an attractive hitchhiker on a lonely country road, who has escaped from the nearby lunatic asylum. Thugs waylay them and force his car to crash. When Hammer returns to semi-consciousness, he hears Christina being tortured until she dies. Hammer, both for vengeance and in hopes that "something big" is behind it all, decides to pursue the case.
Matt, with the assistance of his new friend Riley, is moving out to Los Angeles California to fulfill his dream of making movies. Everything is off to a good start! That is until Matt's childhood best friend Chaps decides to crash the road trip and invite himself along. When old friends don't mix well with new friends, jealousy enters the picture. And if that wasn't enough to put a damper on the road trip, a menacing hitchhiker turns their world upside down leading to a maddening chase that spins wildly out of control.
Steve Morgan kills a man in a holdup and hitches a ride to Los Angeles with Fergie. At a gas station, they pick up two women. Encountering a roadblock, Morgan takes over and persuades the party to spend the night at an unoccupied beach house. The police close in as one by one, the others learn that Morgan is a killer.