An American Indian child, maltreated by her mother and other tribespeople, accompanies her family to a nearby town to buy supplies. There, local white settlers — a couple and their young daughter — befriend the child and give her a doll, her first and only toy. Meanwhile, another tribesman is wantonly killed by a settler. Enraged, the Indians plan revenge and organize a war-party to attack the town. The Indians also take from the child the doll she was given and smash it. The child mourns her broken doll, and buries it with traditional tribal rites. Alarmed that her new friends will be harmed when the town is attacked, the child rushes ahead of the war-party to give warning of the imminent attack. In the raid the child is struck by a bullet, and makes her painful way to her doll’s burial site. Alone, she dies.
Clay Whipple is convicted of murdering the governor following an incident involving a cat's eye pin. Whipple is sentenced to death, but a mentalist named Psychic Jack believes he is innocent since Whipple had been hypnotized at the time of the murder. The psychic persuades the judge to grant the condemned man a retrial, and he sets out to uncover the identity of the real killer, during which time he manages to prevent a second murder from occurring.
A recently widowed and destitute young mother (Jane Novak) appeals to her wealthy and heartless father-in-law (Robert Edeson) for financial aid. Instead, he convinces her to hand over her new baby to his care so that the child will be brought up with "everything money can buy." Unbeknownst to the grandfather, we learn that there are twin sons and our heroine keeps one baby to raise herself. The narrative jumps ahead to the boy's twenty-first birthday and we see what's become of them. Not surprisingly, the wealthy son has grown up spoiled and greedy while the poor one works hard and loves his mother.
Hal Whitney, an irresponsible young millionaire, befriends Timothy Payne, a wise old college professor whose life had been ruined by alcohol. After "adopting" Timothy as his father, Hal introduces him to his sweetheart, Helen Maynard. The outraged Helen breaks their engagement, certain that Timothy will be a bad influence on her hard-drinking fiancé. However, both men assist in each other's reformation, and Hal is soon reunited with Helen, while Timothy marries Hal's mother, Elizabeth, whom he had loved in his youth.
When Richard Barton's health fails, his wife Helen, desperate for money to pay the medical bills, agrees to spend the night with the wealthy Howard Barton, without knowing that he is Richard's long-absent brother. However, after she tells Howard that she is selling herself in order to help her husband, he calls off the rendezvous and sends her home with enough money to pay for Richard's care.
Sato (Sessue Hayakawa) faithfully works for importer James Thornton (James Neill). When the old man dies, he leaves his daughter Mildred (Vivian Martin) in Sato's care. Sato loves the girl, but as he is Japanese he cannot hope to ever marry her (at least not in the racially prejudiced era of the early 1900s). Besides, Mildred loves Harry Maxwell (Tom Forman), who was raised alongside her.
Seduced and abandoned by the caddish Louis La Farge shepherdess Marie Beaupre is cast out of the village and forced to survive in the mountains alone. Driven mad she becomes known as “the witch woman” until hypnotist Dr. Cochefort and his friend Delaunay encounter her while on a hunting trip, take her to Paris, and effectuate a cure at which time she becomes heir to Delaunay's fortune. All seems clear sailing until Marie is introduced to Louis's twin brother Maurice and mistaking him for Louis sets forth on a plan for revenge.
A gangster running a protection racket gets information that he's about to be prosecuted on income-tax-evasion charges. He hires a man with a photographic memory to memorize his books, then destroys them all so the police won't have any evidence to link him to the racket.
Barbara Rand is blinded when she leaps through a window to escape an assailant. Her sister, Natalie, reluctantly abandons her fiancé, Ned Gardiner, and marries Oliver Landis, who can provide the money needed for Barbara's operation. Unaware that Oliver was Barbara's attacker, Natalie blames his business partner, Howard Pollard, who was with Barbara on the night she was injured. Natalie holds Howard at gunpoint, but when her husband arrives, he promises to deal with the villain making sure Howard falls to his death. Upon Barbara’s release from the hospital, Oliver tries to blind her once. Natalie threatens him with a pistol, but Oliver wrests it away from her. He then realizes that he can no longer hide his guilt from Natalie or the police and shoots himself. Barbara has been avenged, and Natalie is free to marry Ned.
Minister John Hodder becomes rector of a prestigious church in the Midwestern city of Bremerton but finds dissension and malfeasance among his congregation. When he calls it out both tragedy and a way forward are revealed.
In a jealous rage dancer Anna Janssen shoots her common-law husband Alastair De Vries in a cafe when she discovers him with a chorus girl. Fleeing to Tahiti she is tracked by detective Thomas McCarthy who arrests her. On their return journey they are marooned on a deserted island. After 2 years together, they realize their love and take marriage vows, but when a ship is sighted, she insists, against his wishes, that she return to face trial.
The quiet life style of Ruth Heck and her brother Lem, who belong to a religious sect called the Seekers, is disrupted when a judge imprisons Lem for a crime he did not commit.
Grace Ainsworth wants to return to her career as an opera singer, and her mother-in-law supports her. Grace's husband, Edwin, wants her to stay at home and to convince her, he relates the story of his latest play about a man who allows his wife to return to the stage. Edwin comes to believe that Grace is in love with Harold Chase, a manager, and the couple separates. Edwin has an affair with a dancer, Madeline, and he winds up in a fight with her dancing partner, Vincenti, which causes him to lose his memory.
Geoffrey Brooke, an African explorer, becomes a friend of Rodney Miller, a struggling young artist. Through his influence Miller becomes celebrated. Brooke is called to the Congo, leaving behind his bride of a few months. Miller is about to despair of finding a suitable model for his supreme artistic effort, a painting of Circe, the temptress, when Cleo, a bewitchingly beautiful woman enters and offers to pose for it.
Jack Pickford got his own production company when his sister Mary signed a huge contract with First National, and this was its first product. the story takes place in the Blue Ridge mountains, where the Appersons and the Yartons have an ongoing feud.
Andrew Maxwell is so intent on creating a universal language that he completely neglects his wife, Laurette, and daughter, Ruth. Laurette decides she wants to return to the stage and is encouraged by Charles Prescott, a former suitor. When Maxwell discovers Laurette and Prescott together, he berates her, and she angrily moves out, taking Ruth along with her.
District Attorney Holden and his special investigator Betty Higgins are trying to convict brothers Joe and Lou Manson, silk-racket hoods, after they are indicted for murder.
Dr. Stannard Wayne -- like all "good" men of the times -- is a God-fearing soul. He marries the former mistress of his friend, Dr. Arthur Richards, without knowing her past. Richards, an abortionist, resumes his affair with the woman and runs off with her. But before he leaves, he frames Wayne for one of the illegal operations he has done, and the innocent man is sent to prison for five years. When he gets out, Wayne has become angry and cynical.
Gordon Palmer is a lazy and cowardly rich man's son. When he and his fiancée, Aileen Merton, are held up by two crooks, Slug Williams and Beef O'Connell, he passively allows them to take whatever they want. At least he comes to life when they try to steal Aileen's engagement ring -- he scares them into giving that back. Aileen, however, is pretty fed up with him.
Nurse Lucy Weston, seeks revenge and marries a young millionaire she believes is responsible for her father's death.