Mexico, 1864. The country is divided by the struggle against the French occupation and emperor Maximilian. The German doctor Karl Sternau and his friend Andreas Hasenpfeffer come to love the country and support the cause of the proud Mexicans.
'The Oilprince' is an unscrupulous businessman. He looks forward to a lucrative deal with the "Western Arizona Bank'. He sells the bank oil wells at Shelly Lake that do actually not exist. The Oilprince learns that the colonists would like to settle at Shelly Lake. So The Oilprince exchanges the scout of the settlers by one of his minions to give them another route. But soon The Oilprince has to recognize that he has not counted on Winnetou, the righteous leader of the Apaches, and his blood brother Old Surehand.
In Apache territory, a supply Army column heads for the next fort, an ex-scout searches for the killer of his Native wife, and a housewife abandons her husband to rejoin her Apache lover's tribe.
At the height of the frontier era, a train races through the Rocky Mountains on a classified mission to a remote army post. But one by one the passengers are being murdered, and their only hope is the mysterious John Deakin, who's being transported to face trial for murder.
The neighbors of a frontier family turn on them when it is suspected that their beloved adopted daughter was stolen from the Kiowa tribe.
Fred Engel's father is murdered by Colonel Brinkley in order to acquire a treasure map, however the Colonel only acquires half of it, the other half as held by Mrs. Butler. Discovering the scene of the crime, Old Shatterhand and Winnetou help Fred bring his father's murderer to justice and locate the treasure of Silver Lake.
An old geezer recalls some of the antics of the citizens of his Western town, more wild and woolly than Tombstone or Dodge City. In this town, they shoot like Stormtroopers, the women seek new meat, and practical jokers abound.
Nevada Smith is the young son of an Indian mother and white father. When his father is killed by three men over gold, Nevada sets out to find them and kill them. The boy is taken in by a gun merchant. The gun merchant shows him how to shoot and to shoot on time and correct.
Farsighted Falcon, chief of the Lakota, seeks refuge in the Black Hills with his wife Blue Hair and two warriors, sole survivors of their tribe. When they are attacked by the outlaw Bashan, Falcon strikes out for the town of Tanglewood to take on Bashan's boss, mining magnate Harrington.
Stodge City is in the grip of the Rumpo Kid and his gang. Mistaken identity again takes a hand as a 'sanitary engineer' named Marshal P. Knutt is mistaken for a law marshal. Being the conscientious sort, Marshal tries to help the town get rid of Rumpo, and a showdown is inevitable. Marshal has two aids—revenge-seeking Annie Oakley and his sanitary expertise.
Two best friends, Clint and Lenny, set out to pan for gold during the California Gold Rush. They have a stroke of luck and find a significant amount of gold in their pans. As they continue to pan, Clint becomes increasingly fixated on finding more and more gold, to the point where he becomes ruthless and starts to turn on Lenny. Lenny tries to remind Clint of the importance of their friendship and the values they once held, but Clint's greed continues to consume him. Eventually, their friendship is put to the test as Clint's behavior becomes increasingly dangerous and erratic. Will the gold be the end of their friendship, or will Lenny be able to save his friend from the destructive power of greed?
As a Civil War veteran spends years searching for a young niece captured by Indians, his motivation becomes increasingly questionable.
In the latter half of the 19th century, gold is discovered in the Black Hills, sacred land of the Lakota people. Gold diggers, profiteers and adventurers flock to the region. Among them is the hard-hearted land speculator Bludgeon, who tries to expel the Lakota using brutal methods. Lakota warriors retaliate, and soon the gold diggers' town becomes a battlefield.
The construction of the Great Western Railroad creates heavy conflict between the railway company and neighboring Indian tribes. Worse, criminal gang leader Santer sets his eyes on a gold mine located on holy Indian land and influences the construction supervisor to re-rout the planned railroad straight through Apache land. Old Shatterhand, who works as a measurement technician, discovers the evil plan and searches contact with the Apaches in an effort to avert war.
Forester, a ruthless oil baron, wants to create a war between the native American tribes and the white men. Old Shatterhand, Winnetou and their sidekick Castlepool try to prevent this.
In early 20th-century Montana, Col. William Ludlow lives on a ranch in the wilderness with his sons, Alfred, Tristan, and Samuel. Eventually, the unconventional but close-knit family are bound by loyalty, tested by war, and torn apart by love, as told over the course of several decades in this epic saga.
The sole survivor of a bloody massacre vows revenge on his attackers and on the men who killed his wife.
Army despatch rider Hondo Lane discovers a woman and her son living in the midst of warring Apaches, and he becomes their protector.
Rollins' gang wants to grab land by inciting the settlers in a war against the Indians but Winnetou and Old Shatterhand try to keep the peace, until Rollins frames Winnetou up for the murder of Jicarilla Chief's son.
Renegades trying to get the army to abandon their fort get the Indians addicted to whiskey, then convince them to attack and drive out the soldiers.