The life of Danny Wright, a salesman forever on the road, veers into dangerous and surreal territory when he wanders into a Mexican bar and meets a mysterious stranger, Julian, who's very likely a hit man. Their meeting sets off a chain of events that will change their lives forever, as Wright is suddenly thrust into a far-from-mundane existence that he takes to surprisingly well … once he gets acclimated to it.
In the 1930s, jazz guitarist Emmet Ray idolizes Django Reinhardt, faces gangsters and falls in love with a mute woman.
A gang of bank robbers with a suitcase full of money go to the desert to hide out. After burying the loot, they find their way to a surreal town full of cowboys who drink an awful lot of coffee.
Carolyn's sorority sisters set their sights on the Sorority of the Year award and coaching challenged athletes is their ticket to the trophy. But when the queen of formals finds herself mentoring Pumpkin, a disabled athlete, their two worlds collide.
The career and personal life of writer Lee are at a standstill, so he divorces his bashful wife, Robin, and dives into a new job as an entertainment journalist. His assignments take him to the swankiest corners of Manhattan, but as he jumps from one lavish party to another and engages in numerous empty romances, he starts to doubt the worth of his work. Meanwhile, top TV producer Tony falls for Robin and introduces her to the world of celebrity.
Marion and Jack try to rekindle their relationship with a visit to Paris, home of Marion's parents — and several of her ex-boyfriends.
The brains of a Russian taxi driver and a wealthy businessman are brought together in one body by a mad scientist.
Obsessive scientist Nathan and his lover, the naturalist Lila, discover Puff: a man born and raised in the wild. As Nathan trains the wild man in the civilized ways of the world, Lila fights to preserve the man’s natural state. In the power struggle that ensues, an unusual love triangle emerges.
Dinner time in a remote home of a prairie family turns nightmarish when a band of blood spattered outlaws break through the front door in search of food, horses, and women. Nothing is as it seems in this constantly twisting genre bender.
A transgender woman takes an unexpected journey when she learns that she had a son, now a teenage runaway hustling on the streets of New York.
Single dad Richard meets Christine, a starving artist who moonlights as a cabbie. They awkwardly attempt to start a romance, but Richard’s divorce has left him emotionally damaged. Meanwhile, Richard’s sons—one a teenager, the other 6-years-old—take part in clumsy experiments with the opposite sex.
Justin Cobb, a teenager in suburban Oregon, copes with his thumb-sucking problem, romance, and his diagnosis with ADHD and subsequent experience using Ritalin.
Matt is a screenwriter whose career is not going especially well and whose personal life is dwindling into nothingness. Matt starts talking with his friends about suicide, and nearly all of them become deeply concerned, convinced his depression has taken him over the edge. Matt insists to all around him that his questions about killing himself are merely part of his research for a script about a man who has turned suicidal. But his ex-girlfriend Amanda is the only one that seems to believe it.
Leslie is left with few options when her husband is sent back to war in the Middle East. A modest amount of help arrives in the form of his brother, Salman, who is less than prepared to care for the couple's two preadolescent boys. When Leslie still can't make ends meet on her own, Salman is forced to find employment, but, with minimal qualifications, his only option is to become a mascot for a digital company by donning a bulbous blue costume.
Soon after his insufferably arrogant father wins the Nobel Prize for chemistry, Barkley Michaelson is kidnapped by Thaddeus James, a young genius who claims to be Barkley's illegitimate half-brother. Motivated not so much by money as revenge, Thaddeus tries to convince Barkley to help him carry out a multimillion-dollar extortion plot against their patriarch.
Gay, alienated Los Angeles teens have a hard time as their parents kick them out of their homes, they don’t have money, their lovers cheat, and they are harassed by gay-bashers.
Charlie thinks he's met the perfect woman, but in order to be with her, he must first get past her dog. Just when he thinks all is lost, he realizes that he loves the dog too! Now he must do everything he can to keep them both.
Six people on the verge of a breakdown decide to check themselves into an insane asylum, only to discover there is just room for one.
An ensemble drama about a married actress, her sister and their myriad sexual and creative temptations.
Various citizens of Toronto anxiously await the end of the world, which is occurring at the stroke of midnight on New Year's Day.