New York City is full of lonely hearts seeking the right match, and what Alice, Robin, Lucy, Meg, Tom and David all have in common is the need to learn how to be single in a world filled with ever-evolving definitions of love.
Gabriel is a young, aspiring musical composer whose life seems stuck in the First Act. When his new musical number gets a critical reception, a theatre colleague, Perry, tells Gabriel that he needs to get a life before he can write about one – so he heads straight for his local gay bar.
College buddies chip in and promise that the group's last unmarried man will collect a cash pot. Seven years later, the kitty is worth $500,000 -- money Michael needs to pay a gambling debt. Problem is, the only other single guy is a hopeless womanizer!
Adam and Steve are two gay youths who have a one-night stand that ends embarrassingly. Nearly two decades later, Adam, now a Manhattan tour guide, and Steve, a psychiatrist, meet again -- but neither remembers the other from years before. The two begin dating, even playing matchmaker for their friends Michael and Rhonda, but their promising relationship hits a major snag when Adam and Steve finally recall their past connection.
At his bachelor party, Jason has a one-night fling with Nikki, a radiant beauty with whom he forms an immediate bond. They agree to keep their secret locked away forever. Two years later, Jason, his wife, Andy and his fiancee plan a reunion weekend. Jason is shocked to discover that Andy's fiancee is Nikki. Now, secret and passionate affairs are played out.
Lovestruck Dustin is dating Alexis, his ideal girlfriend, but when she dumps him for coming on too strong, Dustin takes drastic measures to win her back. He asks his best friend Tank to take her on the worst rebound date imaginable - his side job - so that she will come running back to him, and Tank reluctantly agrees. However, Alexis is more than a match for Tank's shock tactics and he begins to really fall for her, leaving him torn between loyalty to Dustin and his growing attraction toward Alexis.
A woman—pregnant after a one-night stand with her awkward neighbor—sleeps with a businessman to pass off the baby as his.
Cooper is an actor who sees life as one big party, while Ed is in advertising and takes life too seriously. When Ed gets stressed over a deadline he has to meet, his brother Cooper works hard in trying to get his brother hooked up with a girl, thus a long weekend of stress and beautiful women, culminating in Ed meeting, and making love to, the woman of his dreams.
Four pals are stuck in a rut in adulthood: Adam has just been dumped, Lou is a hopeless party animal, Nick is a henpecked husband, and Jacob does nothing but play video games in his basement. But they get a chance to brighten their future by changing their past after a night of heavy drinking in a ski-resort hot tub results in their waking up in 1986.
Cursed since childhood, dentist Charlie Logan cannot find the right woman. Even worse, he learns that each of his ex-girlfriends finds true love with the man she meets after her relationship with him ends. Hearing of Charlie's reputation as a good-luck charm, women from all over line up for a quick tryst. But when Charlie meets the woman of his dreams, he must find a way to break the curse or risk losing her to the next man she meets.
A married man's one-night stand comes back to haunt him when that lover begins to stalk him and his family.
To call or not to call? For young Cora it's not a question. In fact, after the first date you may never call the guy, even if it was the best sex of your life! It's him who must beg for a meeting - and not later than 72 hours after. Otherwise - delete it from memory.
A thirty-something southern woman searches for love, despite the burdens she carries with her.
When actress Sarah Marshall dumps aspiring musician Peter Bretter for rock star Aldous Snow, Peter's world comes crashing down. His best friend Brian suggests that Peter should get away from everything and to fly off to Hawaii to escape all his problems. After arriving in Hawaii and meeting the beautiful receptionist Rachel Jansen, Peter is shocked to see not only Aldous in Hawaii, but also Sarah.
When a young accountant is devastated after discovering his inspiringly beautiful girlfriend is cheating on him, his best friend, who's engaged to a girl he doesn't love, convinces him to go on a "run" and sleep with as many women as he can to get over his heart break.
Holidaymakers arriving in a Club Med camp on the Ivory Coast are determined to forget their everyday problems and emotional disappointments. Games, competitions, outings, bathing and sunburn accompany a continual succession of casual affairs.
Venereal disease forces a confirmed bachelor to take stock of his history of one night stands.
Chen Yu Han is the daughter of Chen group founder. She has a one night stand and gets pregnant with Ye Chen Xi, her father's friend's son and the president of Ye Corporation while both were drunk an are forced to get married. Will this short gun contract marriage survive the schemes of Yi Xuan Xuan, who is in love with Ye Chen Xi and Jin Yang, Yu Han's ex-bf who desperately wants her back?
A player in a famous orchestra finds sexual experiences with a Russian opera singer, which he enjoys much because his wife has just left due to the fact that he has purchased a porno movie. The orchestra player gets known to his neighbour, a gay man having also relationship troubles, and together they are trying hard to find a way how to go on with their lifes.
When Paula leaves her mate Pedro, he misses her and looks for comfort with his best friends, Javier and Sonia. Paula is having an affair with Javier. Pedro tries to find who is the secret lover of Paula, and hires a private eye. Meanwhile, while comforting Pedro, Sonia has a one night stand with him and Javier thinks she is cheating on him with her lesbian friend Luzia.