It is several years after the events of the first movie, and David Herdeg (the survivor of the Philadelphia Experiment from the first film) and Allison (the woman from 1984 he fell in love with) have married and have a child. David awakes, in agony, to a changed world. Germany won World War II and the United States is now about to mark 50 years as a Nazi conquest.
Dr. Eric Vornoff, with the help of his mute assistant Lobo, captures twelve men for a grisly experiment; His goal to turn them into supermen using atomic energy. Reporter Janet Lawton, fiancée of the local lieutenant, vows to investigate Vornoff's supposedly haunted house.
A boy takes in a stray dog, later finding out that it's an ultra-intelligent runaway from a genetic research lab. Unbeknownst to him, the dog is being stalked by another escaped creature that's not quite so friendly.
In 19th century England, a noted brain surgeon rescues a former student from being hanged on a false conviction for murder, and spirits him away to an ancient, repurposed abbey far in the countryside. There, he connives his pupil into assisting him in mapping the functions of the various parts of the human brain, using living subjects who are under a terrible animation-suspending drug called "black sleep". Subsequently, the student, along with the daughter of one of the subjects, discover that most of these subjects have survived but are being kept in a dungeon-like cellar, in various stages of physical and mental derangement...
An oceanic observation station is in desperate trouble after a sudden shark attack wrecked the oxygen supply. The accompanying ship, a coast guard cruiser, and other ships in and around the Bermuda triangle are attacked as well. The US Navy sends a submarine to investigate, but soon they too are under attack.
A rich actress who has gotten too old for leading roles employs a scientist who is working on a formula for eternal youth. The formula involves withdrawing certain fluids from the human brain. She takes the serum, but its unforeseen side effects turn her into a murderous monster.
Dr. Bill Cortner and his fiancée, Jan Compton, are driving to his lab when they get into a horrible car accident. Compton is decapitated. But Cortner is not fazed by this seemingly insurmountable hurdle. His expertise is in transplants, and he is excited to perform the first head transplant. Keeping Compton's head alive in his lab, Cortner plans the groundbreaking yet unorthodox surgery. First, however, he needs a body.
A plane crash surviving attorney stumbles upon a mysterious island and is shocked to discover that a brilliant scientist and his lab assistant have found a way to combine human and animal DNA—with horrific results.
Cocky researcher Sebastian Caine is working on a project to make living creatures invisible. Determined to achieve the ultimate breakthrough, Caine pushes his team to move to the next phase — using himself as the subject. The test is a success, but when the process can't be reversed and Caine seems doomed to future without flesh, he starts to turn increasingly dangerous.
When Seth Brundle makes a huge scientific and technological breakthrough in teleportation, he decides to test it on himself. Unbeknownst to him, a common housefly manages to get inside the device and the two become one.
Exploring the further adventures of Carmen and Juni Cortez, who have now joined the family spy business as Level 2 OSS agents. Their new mission is to save the world from a mad scientist living on a volcanic island populated by an imaginative menagerie of creatures. On this bizarre island, none of the Cortez's gadgets work and they must rely on their wits--and each other--to survive and save the day.
Things spiral out of control in a high school in Manhattan when a terrible accident involving a science experiment injures a kid for life.
In 1989, a breakthrough in "advanced parasitic research" on Cuttyhunk Island gave scientists a jump in human evolution. Initial tests proved promising, as subjects experienced heightened physical and mental strength and awareness. But - something in the experiment went horribly wrong, and the island mysteriously lost three quarters of its population.
Dr. Génessier is riddled with guilt after an accident that he caused disfigures the face of his daughter, the once beautiful Christiane, who outsiders believe is dead. Dr. Génessier, along with accomplice and laboratory assistant Louise, kidnaps young women and brings them to the Génessier mansion. After rendering his victims unconscious, Dr. Génessier removes their faces and attempts to graft them on to Christiane's.
A teacher conducts an experiment in an American high school where students learn how easy it is to be seduced by the same social forces which led to the horrors of Nazi Germany.
A mad scientist crosses plants with people, and the results wind up in a sideshow.
A small island community is overrun with creeping, blobbish, tentacled monsters which liquefy and digest the bones from living creatures. The community struggles to fight back.
A scientist develops a formula which will cause animals to regress to the form of their primitive ancestors, and tries it on himself with disastrous results.
Dr. Laurence, a once-respectable scientist, begins to research the origin of the mind and the soul. The science community rejects him, and he risks losing everything for which he has worked. He begins to use his discoveries to save his research and further his own causes, thereby becoming ... a mad scientist, almost unstoppable.
A group of space renegades hook up with a drifter named McQueen. Together they hole up in an abandoned research facility for the night and are relentlessly pursued by a human/monster hybrid.