With shades of Disturbia, the tale will focus on a group of teens who discover that a neighbor is building a monster in his basement.
Scooby, Shaggy and Scrappy are on their way to a Miss Grimwood's Finishing School for Girls, where they've been hired as gym teachers. Once there, however, they find that not only is it actually an all-girl school of famous monsters' daughters but there's a villainess out to enslave the girls.
Frankenstein, a young medical student, trying to create the perfect human being, instead creates a misshapen monster. Made ill by what he has done, Frankenstein is comforted by his fiancée; but on his wedding night he is visited by the monster.
When Dr Frankenstein decides to retire from the monster-making business, he calls an international roster of monsters to a creepy convention to elect his successor. Everyone is there including Dracula, The Werewolf, The Creature, Dr Jekyll & Mr Hyde and many more. But Frankenstein's title is not all that is at stake. The famous doctor has also discovered the secret of total destruction that must not fall into the wrong hands!
Dracula, Werewolf, and the Invisible Man must work together to stop Dr. Frankenstein from creating an unstoppable monster.
Young couple Scott and Mary are on their way to a Halloween party when their car breaks down, and they encounter a creepy castle where Dr. Frankenstein seeks to put Scott's brain in his monstrous creation. As for Mary, Count Dracula wants her for his mistress.
A mad scientist creates a monster called "Mosaico," who breaks out of the laboratory to hunt down and kill beautiful women.
Dr. Victor Frankenstein creates a monster to show his scientific theories, but soon leaves him. So the scientist tries to rebuild his life getting married with Janet, and retires to his castle with Igor. However the monster comes back to haunt Frankenstein, and so Victor finds out that the monster has ferocious sexual orientation to Janet. Frankenstein then calls the servant Igor to readjust the monster, but also Igor takes advantage of Janet...
A single mother and a childless morgue technician are bound together by their relationship to a little girl they have reanimated from the dead.
The Wolf Man tries to warn a dimwitted porter that Dracula wants his brain for Frankenstein monster's body.
Frankenstein's unscrupulous colleague, Dr. Bohmer, plans to transplant Ygor's brain so he can rule the world using the monster's body, but the plan goes sour when he turns malevolent and goes on a rampage.
Blackmailing a young couple to assist with his horrific experiments the Baron, desperate for vital medical data, abducts a man from an insane asylum. On route the abductee dies and the Baron and his assistant transplant his brain into a corpse. The creature is tormented by a trapped soul in an alien shell and, after a visit to his wife who violently rejects his monstrous form, the creature wreaks his revenge on the perpetrator of his misery: Baron Frankenstein.
Grave robbers open the grave of the wolf man and awaken him. He doesn't like the idea of being immortal and killing people when the moon is full so tries to find Dr. Frankenstein, in the hopes that the doctor can cure him. Dr. Frankenstein has died; however, his monster is found.
One of the sons of late Dr. Henry Frankenstein finds his father's ghoulish creation in a coma and revives him, only to find out the monster is controlled by Ygor who is bent on revenge.
Baron Victor Frankenstein has discovered life's secret and unleashed a blood-curdling chain of events resulting from his creation: a cursed creature with a horrid face — and a tendency to kill.
Deranged scientist, Gustav Niemann, escapes from prison and overtakes the director of a traveling chamber of horrors, soon reviving the infamous Count Dracula, the frozen Frankenstein Monster, and the Wolf Man.
A deformed tormented girl drowns herself after her lover is framed for murder and guillotined. Baron Frankenstein, experimenting with the transfer of souls, places the boy's soul into her body, bringing Christina back to life. Driven by revenge, she carries out a violent retribution on those responsible for both deaths.
Dr Simon Helder, sentenced to an insane asylum for crimes against humanity, recognises its director as the brilliant Baron Frankenstein, the man whose work he had been trying to emulate before his imprisonment. Frankenstein utilises Helder's medical knowledge for a project he has been working on for some time. He is assembling a man from vital organs extracted from various inmates in the asylum. And the Baron will resort to murder to acquire the perfect specimens for his most ambitious project ever.
Earl Williams is a dreamer teenager obsessed with monsters, who fantasizes his life as if he were living in the world of the monsters of Universal Studios. Although being an excellent student, his intolerant and nasty school teacher Mrs. Perdue does not like him and punishes him for any minor fault. His supportive father Les Williams is also a dreamer, who has never been successful in life. When his father dies, his mother becomes lost with two boys, and tries to change the behavior of Earl. One day, the boy finds the "true Frankenstein" lost by a Carnival, and decides to bring the monster back to life.
When Dr. Frankenstein is killed by a monster he created, his daughter and his lab assistant continue his experiments.