A shy but ambitious film student falls into an intense, emotionally fraught relationship with a charismatic but untrustworthy older man.
Two childhood friends from South Boston turn to crime as a way to get by, ultimately causing a strain in their personal lives and their friendship.
An unnamed man narrates the downward trajectory of his life from beyond the grave, from delinquency to the string of fateful decisions and foolhardy moves that tied him inextricably to the opiate that was the elusive love of his life.
The son of a wealthy businessman finds solace in drugs and alcohol when he breaks up with his childhood love.
January 1978. After their success in England, the punk rock band Sex Pistols venture out on their tour of the southern United States. Temperamental bassist Sid Vicious is forced by his band mates to travel without his troubled girlfriend, Nancy Spungen, who will meet him in New York. When the band breaks up and Sid begins his solo career in a hostile city, the turbulent couple definitely falls into the depths of drug addiction.
A young woman who has been in and out from rehab for the past 10 years returns home for the weekend for her sister's wedding.
By the year 2056, an epidemic of organ failures has devastated the planet. The megacorporation GeneCo provides organ transplants on a payment plan - and those who can’t fulfill their plans have their organs repossessed. In the midst of this, a sickly teenager discovers a shocking secret about herself, her father, and their connection to GeneCo.
Hotshot real estate salesman Daryl has a bad cocaine habit. After embezzling his company's money, he wakes up next to a girl who overdosed. To hide from the police, he checks into a rehabilitation program guaranteeing anonymity. Under the mentorship of counselor Craig, Daryl accepts that he has a substance abuse problem. As he falls in love with fellow patient Charlie, Daryl begins committing to a newly sober life.
A group of career criminals finds itself trapped in a warehouse with the law – and an Attack Dog named DeNiro closing in.
A young boy trying to deal with his mother's heroin addiction befriends a waitress who helps him cope with the tough situation.
After a tragic series of events in his life, Rob discovers the over-the-counter drug known as codeine. The effects of the pill are so strong and addictive, that soon, Rob becomes dependant and consumes them daily. But the less he feels the more he misses, as his life degrades into a deep, dangerous, oblivion of bliss.
One man's love is personified in superhero form inside the mind of his drug addicted girlfriend as she goes through withdrawal.
Eli Johnson struggles through high school challenged by his self-loathing and the pressure to be "normal". The recent passing of his mother due to terminal cancer leaves Eli and his father disconnected and in the dark. Bullied by his peers, Eli turns to prescription drugs to cope with his suicidal thoughts. Falling hopelessly for the popular Addison McKnight, he looks to his love for her as an escape out of his deep depression.
When Albers takes his drug-addicted opera star sister Gerda to a sanitarium, they both become targets of slimy dope peddler Peter Lorre, who fears that Gerda will blow the whistle on him. Lorre kidnaps the woman, leading Albers on a frantic chase.
Stripped of his medical license after performing an operation while high on amphetamines, famed LA surgeon Dr Eugene Sands abandons his former life only to find himself crossing paths with Raymond Blossom, an infamous counterfeiter. Employed as a "gun-shot doctor" when Raymond's associates cannot risk visiting a hospital, Eugene is lured deep into the criminal world and becomes entangled with his boss's girlfriend.
A substance-addicted actress tries to look on the bright side even as she's forced to move back in with her mother to avoid unemployment.
A fifteen year old girl Senka, comes from a wealthy family whose parents enroll in an elite school where she meets a drug dealer with whom he falls in love, and so it has hitherto completely unknown world. Senka is a young and inexperienced girl who, unwittingly, in his new world, the world of drug addiction and pulled his best friend.
In 1965, a young woman with dreams of becoming a writer has a son at the age of 15 and struggles to make things work with the drug-addicted father.
A young man Nuno, tries to understand how his fate is tied to that of his deceased uncle Nuno, whom he never met.
When a former equestrian champion returns home from college, she finds that her best friend is taking her place training for an upcoming competition. As she struggles with the injury that prevents her from riding again, the tension between the two mounts and their trainer encourages them to lean on each other, and their love of horses and racecars, to find strength, hope, and redemption.