Through a series of misunderstandings, Alvin, Simon and Theodore come to believe that Dave is going to propose to his new girlfriend in New York City - and dump them. They have three days to get to him and stop the proposal.
Raoul Duke and his attorney Dr. Gonzo drive a red convertible across the Mojave desert to Las Vegas with a suitcase full of drugs to cover a motorcycle race. As their consumption of drugs increases at an alarming rate, the stoned duo trash their hotel room and fear legal repercussions. Duke begins to drive back to L.A., but after an odd run-in with a cop, he returns to Sin City and continues his wild drug binge.
On a stormy night, young Jim, who transports a luxury car from Chicago to California to deliver it to its owner, feeling tired and sleepy, picks up a mysterious hitchhiker, who has appeared out of nowhere, thinking that a good conversation will help him not to fall asleep. He will have enough time to deeply regret such an unmeditated decision.
Following the arrest of her mother, Ramona, young Vanessa Lutz decides to go in search of her estranged grandmother. On the way, she is given a ride by school counselor Bob Wolverton. During the journey, Lutz begins to realize that Bob is the notorious I-5 Killer and manages to escape by shooting him several times. Wounded but still very much alive, Bob pursues Lutz across the state in this modern retelling of Little Red Riding Hood.
Wildcatter Johnny Maverick and his pal go to a town in oil country offering $25,000 to the person who brings in the first well. They find oil on the outskirts but have to sell a share to a promoter who hires Johnny's old enemy.
Charles and Meg, a young couple whose relationship is currently experiencing some distress, go on vacation in Paestum hoping to mend their problems. But along the way they pick up an aggressive and unscrupulous hitchhiker.
Matt, with the assistance of his new friend Riley, is moving out to Los Angeles California to fulfill his dream of making movies. Everything is off to a good start! That is until Matt's childhood best friend Chaps decides to crash the road trip and invite himself along. When old friends don't mix well with new friends, jealousy enters the picture. And if that wasn't enough to put a damper on the road trip, a menacing hitchhiker turns their world upside down leading to a maddening chase that spins wildly out of control.
Chasing a memory, Alex is determined to drive cross-country to Melbourne. Planning on having just the highway for company, he reluctantly picks up a hitchhiker running from something with as much determination as Alex is running to something.
While driving through the New Mexico Desert during a rainy night, college students Jim Halsey and his girlfriend Grace Andrews give a ride to a hitchhiker. While in their car, the stranger proves to be a psychopath threatening the young couple with a knife, but Jim successfully throws him out of the car. This sets off a chain of events that will change all of their lives forever.
Mere seconds before the Earth is to be demolished by an alien construction crew, Arthur Dent is swept off the planet by his friend Ford Prefect, a researcher penning a new edition of "The Hitchhiker's Guide to the Galaxy."
A woman on the run from her abusive husband encounters a mysterious hitch-hiker.
Driving through the desert en route to San Francisco, Sebastian has a chance encounter with Helena, a mysterious and attractive hitchhiker. Together they embark on a journey to the unknown, testing the boundaries of reality along the way.
Zia, distraught over breaking up with his girlfriend, decides to end it all. Unfortunately, he discovers that there is no real ending, only a run-down afterlife that is strikingly similar to his old one, just a bit worse. Discovering that his ex-girlfriend has also "offed" herself, he sets out on a road trip to find her.
A young man is in a race against time as he searches for a cure after becoming infected with a virus that will eventually turn him into a blood-sucking vampire.
Kowalski works for a car delivery service, and takes delivery of a 1970 Dodge Challenger to drive from Colorado to San Francisco. Shortly after pickup, he takes a bet to get the car there in less than 15 hours.
On their way to an afternoon on the lake, husband and wife Andrzej and Krystyna nearly run over a young hitchhiker. Inviting the young man onto the boat with them, Andrzej begins to subtly torment him; the hitchhiker responds by making overtures toward Krystyna. When the hitchhiker is accidentally knocked overboard, the husband's panic results in unexpected consequences.
A high school senior drives cross-country with his best friends to hook up with a babe he met online.
Taking a break from their dreary lives, close friends Thelma and Louise embark on a short weekend trip that ends in unforeseen incriminating circumstances. As fugitives, both women rediscover the strength of their bond and their newfound resilience.
A bickering couple driving cross-country pick up a murderous hitchhiker who threatens to kill them unless they take him to a sanctuary. In return he agrees to split some bank loot he has on him.
When miner Charley 'Boomer' Baxter sets off a series of massive mining detonations in West Virginia, a gigantic earthquake is soon rocking the North Atlantic, exposing a deep seismic fault that runs the length of the North American continent. Joining forces with government seismology expert Dr Amy Lane, Boomer must now race against time to stop the chasm that is threatening to tear America - and the entire world - in half.