On a stormy night, young Jim, who transports a luxury car from Chicago to California to deliver it to its owner, feeling tired and sleepy, picks up a mysterious hitchhiker, who has appeared out of nowhere, thinking that a good conversation will help him not to fall asleep. He will have enough time to deeply regret such an unmeditated decision.
While driving through the New Mexico Desert during a rainy night, college students Jim Halsey and his girlfriend Grace Andrews give a ride to a hitchhiker. While in their car, the stranger proves to be a psychopath threatening the young couple with a knife, but Jim successfully throws him out of the car. This sets off a chain of events that will change all of their lives forever.
On a road trip across Italy, recent high school graduates Ira, Malin and Ka pick up the intriguing backpacker Zoe. As the four girls stumble across an abandoned village, they start to experiment with the limits of their newly found freedom, away from the expectations of their parents and teachers.
After FBI agent Frank Lacrosse believes his son was kidnapped by a notorious serial killer, he travels to Amarillo, Texas, where he believes the murderer is in hiding. Although officially taken off the case because of its personal significance to him, Frank continues to pursue the killer, causing concern for local sheriff Buck Olmstead. When another victim pops up at a nearby car garage, Frank knows that he is as close as he'll ever be to tracking down the elusive killer.
On their way to an afternoon on the lake, husband and wife Andrzej and Krystyna nearly run over a young hitchhiker. Inviting the young man onto the boat with them, Andrzej begins to subtly torment him; the hitchhiker responds by making overtures toward Krystyna. When the hitchhiker is accidentally knocked overboard, the husband's panic results in unexpected consequences.
Following the arrest of her mother, Ramona, young Vanessa Lutz decides to go in search of her estranged grandmother. On the way, she is given a ride by school counselor Bob Wolverton. During the journey, Lutz begins to realize that Bob is the notorious I-5 Killer and manages to escape by shooting him several times. Wounded but still very much alive, Bob pursues Lutz across the state in this modern retelling of Little Red Riding Hood.
Through a series of misunderstandings, Alvin, Simon and Theodore come to believe that Dave is going to propose to his new girlfriend in New York City - and dump them. They have three days to get to him and stop the proposal.
Kowalski works for a car delivery service, and takes delivery of a 1970 Dodge Challenger to drive from Colorado to San Francisco. Shortly after pickup, he takes a bet to get the car there in less than 15 hours.
One evening, Hammer gives a ride to Christina, an attractive hitchhiker on a lonely country road, who has escaped from the nearby lunatic asylum. Thugs waylay them and force his car to crash. When Hammer returns to semi-consciousness, he hears Christina being tortured until she dies. Hammer, both for vengeance and in hopes that "something big" is behind it all, decides to pursue the case.
Rick Robinson, a law intern, is scheduled to take the bar exam in just four days. Anxious to score points with his boss Mr. McAllister, Rick unwisely agrees to help the man move. The next day, Rick finds himself in a moving van from Miami to Los Angeles, accompanied by McAllister's spoiled niece and her pet pig.
Wildcatter Johnny Maverick and his pal go to a town in oil country offering $25,000 to the person who brings in the first well. They find oil on the outskirts but have to sell a share to a promoter who hires Johnny's old enemy.
Three macabre tales from the latest issue of a boy's favorite comic book, dealing with a vengeful wooden Native American, a monstrous blob in a lake, and an undying hitchhiker.
After a group of Texas teenagers leave prom night early and get into a car crash in the woods, they employ the aid of a nearby insurance agent, who calls in her tow truck-driving boyfriend, Vilmer Slaughter. Unfortunately for them, Vilmer is a sadistic killer with a mechanical leg who introduces them to his brother, Leatherface, and the rest of their twisted family.
The life of Al Roberts, a pianist in a New York nightclub, turns into a nightmare when he decides to hitchhike to Los Angeles to visit his girlfriend.
A sadistic serial killer terrorizes a couple driving on a rural highway in Texas while killing numerous people and framing them for his killings.
Steve Morgan kills a man in a holdup and hitches a ride to Los Angeles with Fergie. At a gas station, they pick up two women. Encountering a roadblock, Morgan takes over and persuades the party to spend the night at an unoccupied beach house. The police close in as one by one, the others learn that Morgan is a killer.
In this Franco-Italian gangster parody, a shopkeeper on his way to an Italian holiday suffers a crash that totals his car. The culprit can only compensate his ruined trip by driving an American friend's car from Naples to Bordeaux, but as it happens to be filled with such contraband as stolen money, jewelry and drugs, the involuntary and unwitting companions in crime soon attract all but recreational attention from the "milieu".
Four college friends take a fateful road trip. The road, Hell's Highway--a direct route to terror. They pick up Lucinda: A hot young hitchiker, full of sexual deviance and lust for the bloody kill. After being terrorized and nearly killed, the group manages to turn the tables. They thought they killed her, but around the next ben--around every ben-- she appears like a mirage ready to murder again. Is she the devil? Can anyone stop her killing spree?
Monette, a recently separated travelling book salesman tells his grim story to both a priest and a hitchhiker, looking for absolution.
A young woman stumbles into a nightmare land of hijacking and humiliation while driving cross-country from California to New York.