Leonard Shelby is tracking down the man who raped and murdered his wife. The difficulty of locating his wife's killer, however, is compounded by the fact that he suffers from a rare, untreatable form of short-term memory loss. Although he can recall details of life before his accident, Leonard cannot remember what happened fifteen minutes ago, where he's going, or why.
Who is the mysterious stranger Cecilia met on the street? Why is he suspicious of everyone? She is happily married, has a lovely child and a good job: yet she decides to join him and to become his lover, sharing his destiny right up to its tragic conclusion.
A self-assured businessman murders his employer, husband of his mistress, which unintentionally provokes an ill-fated chain of events.
Peter Winter is a young schizophrenic who is desperately trying to get his daughter back from her adoptive family. He attempts to function in a world that, for him, is filled with strange voices, electrical noise, disconcerting images, and jarringly sudden emotional shifts. During his quest, he runs afoul of the law and an ongoing murder investigation.
Mort Rainey, a writer just emerging from a painful divorce with his ex-wife, is stalked at his remote lake house by a psychotic stranger and would-be scribe who claims Rainey swiped his best story idea. But as Rainey endeavors to prove his innocence, he begins to question his own sanity.
In 1989, prostitute Aileen Wuornos befriends and enters a relationship with a young woman named Selby. Determined to straighten out her life, Aileen's limited education lands her back on the corner. She's raped by a trick, who she kills. A string of murder and robbery follows that ultimately leads Aileen to becoming America's first female serial killer.
When larcenous real estate clerk Marion Crane goes on the lam with a wad of cash and hopes of starting a new life, she ends up at the notorious Bates Motel, where manager Norman Bates cares for his housebound mother.
A transgender woman takes an unexpected journey when she learns that she had a son, now a teenage runaway hustling on the streets of New York.
A tormented jazz musician finds himself lost in an enigmatic story involving murder, surveillance, gangsters, doppelgängers, and an impossible transformation inside a prison cell.
Humbert Humbert is a middle-aged British novelist who is both appalled by and attracted to the vulgarity of American culture. When he comes to stay at the boarding house run by Charlotte Haze, he soon becomes obsessed with Lolita, the woman's teenaged daughter.
Jesse, a small-time criminal, high-tails it to Los Angeles to rendezvous with a French exchange student. Stealing a car and accidentally killing a highway patrolman, he becomes the most wanted fugitive in L.A.
Reporter John Klein is plunged into a world of impossible terror when fate draws him to the sleepy West Virginia town of Point Pleasant, whose residents are being visited by a great winged shape that sows hideous nightmares and fevered visions.
The murderous, backwoods Firefly family take to the road to escape the vengeful Sheriff Wydell, who is not afraid of being as ruthless as his target.
Seville, Spain. Juan Santos, a convicted petty criminal, gets out of jail for a day to celebrate with Triana, his wife, the first communion of their daughter Estrella.
Two FBI agents investigating the murder of civil rights workers during the 60s seek to breach the conspiracy of silence in a small Southern town where segregation divides black and white. The younger agent trained in FBI school runs up against the small town ways of his partner, a former sheriff.
Complete strangers stranded at a remote desert motel during a raging storm soon find themselves the target of a deranged murderer. As their numbers thin out, the travelers begin to turn on each other, as each tries to figure out who the killer is.
A German woman named Jasmin stumbles upon a dilapidated motel/diner in the middle of nowhere. Her unusual appearance and demeanor are at first suspicious to Brenda, the exasperated owner who has difficulty making ends meet. But when an unlikely magic sparks between the two women, this lonely desert outpost is transformed into a thriving and popular oasis.
Kyung-jin, a police officer who finds herself chasing down a suspected bag-snatcher on her day off. However, the man she catches turns out to be Myungwoo, a passer-by who was himself trying to apprehend the real criminal.
In the midst of his crumbling relationship, a radio show host begins speaking to his biggest fan—a young boy—via the telephone. But when questions about the boy's identity come up, the host's life is thrown into chaos.
Lake Tahoe, 1969. Seven strangers, each one with a secret to bury, meet at El Royale, a decadent motel with a dark past. In the course of a fateful night, everyone will have one last shot at redemption.