The Law Enforcement Technology Advancement Centre (LETAC) has developed SID version 6.7: a Sadistic, Intelligent, and Dangerous virtual reality entity which is synthesized from the personalities of more than 150 serial killers, and only one man can stop him.
While working on a thesis about audiovisual violence, film student Ángela finds a snuff video where a girl is tortured until death. Soon she discovers that she was a former student in her university, and that the authors of the video are not very far either.
Homicide detective John Hobbes witnesses the execution of serial killer Edgar Reese. Soon after the execution the killings start again, and they are very similar to Reese's style.
Thomas Krömer follows the traces of a brutal murder in werewolf-manner out of personal interest. After investigating for some time, the traces all point to one person: himself. Now, he has to find out whether he surprisingly turns into a blood-seeking werewolf at full moon without knowing it or if there is an other solution to the murders. Police are getting pretty suspicious after Thomas' own grandmother has been brutally slaughtered in her little fairy-tale-fashioned house in the woods, and it will soon be time for a full moon...
Forensic psychologist and detective Alex Cross travels to North Carolina and teams with escaped kidnap victim Kate McTiernan to hunt down "Casanova," a serial killer who abducts strong-willed women and forces them to submit to his demands. The trail leads to Los Angeles, where the duo discovers that the psychopath may not be working alone.
Former FBI Agent Will Graham, who was once almost killed by the savage Hannibal 'The Cannibal' Lecter, now has no choice but to face him again, as it seems Lecter is the only one who can help Graham track down a new serial killer.
On a stormy night, young Jim, who transports a luxury car from Chicago to California to deliver it to its owner, feeling tired and sleepy, picks up a mysterious hitchhiker, who has appeared out of nowhere, thinking that a good conversation will help him not to fall asleep. He will have enough time to deeply regret such an unmeditated decision.
A young pathologist seeks answers to the mysterious death of a friend and soon comes into contact with the same cursed videotape that caused the death of the friend's wife and son, which is haunted by the curse of Sadako, a relentless spirit.
Three converging story lines involving bootleggers, a serial killer and drug dealers are followed. A former drug dealer tries to go straight, but comes across a stash of stolen drugs. Meanwhile, a middle-aged suburban housewife hides a sadistic and vicious streak.
What goes through the mind of a serial killer as he meticulously plots his crimes, researching his victims and entrapping them while they are none the wiser?
Lincoln Rhyme was the department's top homicide detective and leading expert in criminal forensics until an injury left him paralyzed, depressed, and incapable of working. But when a gruesome murder in Manhattan leaves detectives baffled, they call on Rhyme to help solve the mystery. Amelia Donaghy, a rookie cop whose quick thinking preserved a gruesome murder scene, is enlisted by Rhyme to be his on-the-scene forensics expert. With Amelia reluctantly acting as Rhyme's able-bodied go-between, the pair piece together cryptic clues the killer leaves behind at the scene of the crime, hoping to catch the grisly serial killer.
Jason Voorhees is tracked down and blown to bits by a special FBI task force, reborn with the bone-chilling ability to assume the identity of anyone he touches.
A disgraced FBI agent with a drinking problem joins nine other troubled law enforcement officers at an isolated detox clinic in the wilds of Wyoming. But the therapeutic sanctuary becomes a nightmarish hellhole when a major snowstorm cuts off the clinic from the outside world and enables a killer on the inside to get busy.
Norman Bates is declared sane and released from the facility in which he was being held, despite the complaints of Lila Loomis, sister of his most famous victim. Is he really cured, or will he kill again?
Rachel is a criminology student hoping to land a position as a teacher's assistant for professor Robert Starkman. She's sure this position will pave the way to an FBI career, and she's willing to do anything to obtain it -- including killing her classmates. The school psychiatrist, Dr. Daniels, becomes aware that Rachel is insane, but Rachel is skilled at her dangerous game of death and identity theft.
FBI agent Joel Campbell, burnt-out and shell-shocked after years spent chasing serial killers, flees L.A. to begin a new life for himself in Chicago. But five months later, Joel's best laid plans are abruptly cut short when his new hometown becomes the setting for some particularly gruesome murders--murders that could only have been committed by one man: David Allen Griffin. One of Joel's most elusive and cunning nemeses, Griffin has followed his former pursuer to Chicago in order to play a sadistic game of cat and mouse. Taunting Joel with photographs of his intended victims and leaving his crime scenes meticulously free of clues in order to keep the police at bay, Griffin derives as much pleasure out of watching Joel react to every movement as watching his victims die. But when Griffin moves into Joel's inner circle, Joel must quickly find some way to stop him before someone close to him becomes the next one to die.
Arriving in Chicago, Henry moves in with ex-con acquaintance Otis and starts schooling him in the ways of the serial killer.
Zoe is abducted by a suburban single mother named Alina, who just so happens to be a deranged yet altruistic serial killer. As Zoe battles for survival, she finds herself asking what in her life is even worth fighting for.
A lawyer is asked to come to the police station to clear up a few loose ends in his witness report of a foul murder. "This will only take ten minutes", they say, but it turns out to be one loose end after another, and the ten minutes he is away from his speech become longer and longer.
Chrissie and her friends set out on a road trip for a final fling before one is shipped off to Vietnam. Along the way, bikers harass the foursome and cause an accident that throws Chrissie from the vehicle. The lawman who arrives on the scene kills one of the bikers and brings Chrissie's friends to the Hewitt homestead, where young Leatherface is learning the tools of terror.