An obsessed scientist conducts profane experiments in evolution, eventually establishing himself as the self-styled demigod to a race of mutated, half-human abominations.
Tampering with life and death, Henry Frankenstein pieces together salvaged body parts to bring a human monster to life; the mad scientist's dreams are shattered by his creation's violent rage as the monster awakens to a world in which he is unwelcome.
Professor Frankenstein creates a teenager from an accident victim, who gets angry when he learns he is going to be taken apart.
A mad scientist creates a monster called "Mosaico," who breaks out of the laboratory to hunt down and kill beautiful women.
A mad doctor uses a fake taxi driver to kidnap victims and then removes their eyes in hopes of perfecting an eye transplant that will allow his blind wife to see again. One of the doctor's servants ends up getting possessed by not one, but several of the victims.
After having a feud with director Kenneth J. Hall, producer Fred Olen Ray hired Ted Newsom to shoot brand new footage (on video) to weave in with scenes from Hall's film Evil Spawn (1987).
A plastic surgeon goes mad when he discovers that his wife have an affair. He fakes her death and disfigure her and locks her in the cellar.
Stefan learns that his invalid grandmother was the nurse/lover of Nazi doctor Franz Kindler and that she removed his brain when the Nazis were losing WW2. Unable to successfully perform a transplant on test subjects, she needs Stefan to carry on for her now that her health is failing.
The eminent Dr. Phibes awakens from a decade of suspended animation and heads to Egypt with the corpse of his dead wife, which he intends to resurrect by murdering people in strange and heinous ways.
An ex-vaudeville actor is working as the assistant to a doctor who has Frankenstein aspirations. The ex-vaudeville actor kills the doctor and decides to assume the identity of the dead physician.
A brilliant but deranged neurosurgeon becomes obsessively fixated on a judge's daughter. With the help of an escaped criminal whose face he has surgically deformed, the mad man lures her, her father, and her fiancé to his isolated castle-like home, where he has created a torture chamber with the intent of torturing them for having 'tortured' him.
University professor George Kingsley is struck by gangsters while crossing the street, leaving him with brain damage and one of the gangsters, Cannon, paralyzed. Kingsley's friend Dr. Sovac attends to both men, and when Cannon offers him a reward for aiding his recovery, Kovac transplants part of Cannon's brain into the dying Kingsley's skull, creating a dual personality.
A scientist takes the brain of dead man and revives it via electrodes as it lays suspended in a tank of liquid. Soon, the brain grows to possess enormous psychic powers and inflicts its personality upon the doctor who saved it, creating a "Jekyll and Hyde" paradigm.
A hypnotherapist uses a temperamental teenager as a guinea pig for a serum which transforms him into a vicious werewolf.
The year is 1885, and necrophiliac Dr. Hitchcock likes to drug his wife for sexual funeral games. One day he accidentally administers an overdose and kills her. Several years later he remarries, with the intention of using the blood of his new bride to bring his first wife's rotting corpse back to life.
A fugitive doctor tries to raise the dead for South Sea Islanders.
Dr. Hohner, theatre physician at the Vienna Royal Theatre, murders his mistress, the star soprano when his jealousy drives him to the point of mad obsession. Ten years later, another young singer reminds Hohner of the late diva and his old mania kicks in. Hohner wants to prevent her from singing for anyone but him, even if it means silencing her forever.
Following his forced retirement from an appalling rock band, Jason decides to vacation at Brittlehouse Manor, a health farm run by the leather-gloved, ex-Nazi scientist Dr. Storm. Along the way, Jason meets Judy, also on her way to Brittlehouse Manor to visit her aunt, who married Dr. Storm some years ago. Once they arrive, the pair realise rather quickly that something is wrong, probably because the other guests have had their brains surgically removed, or all the blood pouring from the sink, or possibly just because the creepy midget keeps telling them to brush their teeth.
A scientist working on cures for rare afflictions, such as a bone softening agent made from molds to allow him to correct the spinal deformity of his nurse, finds the physical causes of lycanthropy in wolf-man Larry Talbot and of vampirism in Count Dracula, but himself becomes afflicted with homicidal madness while exchanging blood with Dracula.
Dr. Leon Kravaal develops a potential cure for cancer, which involves freezing the patient. But an experiment goes awry when authorities believe Kravaal has killed a patient. Kravaal freezes the officials, along with himself. Years later, they are discovered and revived in hopes that Kravaal can indeed complete his cure. But human greed and weakness compound to disrupt the project.