Confined to a mental hospital, young Kirsty Cotton insists her supposedly dead father is stuck in hell, controlled by sadomasochistic demons after being betrayed by his evil, occult-obsessed wife, Julia. Few believe Kirsty, except the thrill-seeking Dr. Channard, who is intrigued by the young woman's lurid stories. So when Kirsty and fellow patient Tiffany head to hell for a rescue, Channard and Julia are close behind.
An ex-vaudeville actor is working as the assistant to a doctor who has Frankenstein aspirations. The ex-vaudeville actor kills the doctor and decides to assume the identity of the dead physician.
After Malukan immigrants engage in a string of corpse mutilations at various New York City hospitals, a doctor and a morgue assistant travel to the Maluku Islands to investigate.
An obsessed scientist conducts profane experiments in evolution, eventually establishing himself as the self-styled demigod to a race of mutated, half-human abominations.
Tampering with life and death, Henry Frankenstein pieces together salvaged body parts to bring a human monster to life; the mad scientist's dreams are shattered by his creation's violent rage as the monster awakens to a world in which he is unwelcome.
Professor Frankenstein creates a teenager from an accident victim, who gets angry when he learns he is going to be taken apart.
A mad scientist creates a monster called "Mosaico," who breaks out of the laboratory to hunt down and kill beautiful women.
A mad doctor uses patients at his isolated psychiatric institute as subjects in his attempts to create longevity by surgically installing an artificial gland in their skulls.
Dr. Bonner plans to live forever through periodic gland transplants from younger, healthier human victims. Bonner looks about 40; he's really 104 years old. But people are starting to get suspicious, and he may not make 200.
Following his forced retirement from an appalling rock band, Jason decides to vacation at Brittlehouse Manor, a health farm run by the leather-gloved, ex-Nazi scientist Dr. Storm. Along the way, Jason meets Judy, also on her way to Brittlehouse Manor to visit her aunt, who married Dr. Storm some years ago. Once they arrive, the pair realise rather quickly that something is wrong, probably because the other guests have had their brains surgically removed, or all the blood pouring from the sink, or possibly just because the creepy midget keeps telling them to brush their teeth.
A scientist working on cures for rare afflictions, such as a bone softening agent made from molds to allow him to correct the spinal deformity of his nurse, finds the physical causes of lycanthropy in wolf-man Larry Talbot and of vampirism in Count Dracula, but himself becomes afflicted with homicidal madness while exchanging blood with Dracula.
A mad doctor (Bela Lugosi) and his helpers (John Carradine, George Zucco) lure girls to his lab for brain work, to help his wife.
An insane surgeon's obsession with an actress leads him to replace her wounded pianist husband's hands with the hands of a knife murderer--hands which still have the urge to throw knives.
In "Multo", a young groom in Baguio for his honeymoon is possessed by a homicidal spirit when he discovers a cursed ring and decides to wear it. "Kulam" is set in the eerie halls of a mysterious hospital where a doctor practice voodoo and dead bodies go wandering in the night. "Aswang" is about a student who is a guest at a town fiesta in a remote province. The people's hospitable ways leave her clueless about a ritual that takes place at night.
A fugitive, dangerous madman reaches an English village where he confronts his former partner who left him for dead in the jungle after their discovery of a diamond mine. When the former partner also claims to have since lost the mine and all its wealth, which he took all for himself, and though the partmer is still living in a state of luxury , the madman takes up an offer from a crazed scientist to make him invisible, something the scientist has already done with experimental animals, so that he can take revenge.
In 19th century England, a noted brain surgeon rescues a former student from being hanged on a false conviction for murder, and spirits him away to an ancient, repurposed abbey far in the countryside. There, he connives his pupil into assisting him in mapping the functions of the various parts of the human brain, using living subjects who are under a terrible animation-suspending drug called "black sleep". Subsequently, the student, along with the daughter of one of the subjects, discover that most of these subjects have survived but are being kept in a dungeon-like cellar, in various stages of physical and mental derangement...
Dr. Leon Kravaal develops a potential cure for cancer, which involves freezing the patient. But an experiment goes awry when authorities believe Kravaal has killed a patient. Kravaal freezes the officials, along with himself. Years later, they are discovered and revived in hopes that Kravaal can indeed complete his cure. But human greed and weakness compound to disrupt the project.
The doctor is back! And this time, she’s cloned herself to make an army of unstoppable warriors!
An unnamed doctor has always had everything he's ever wanted, but that has only made him develop more extreme and depraved needs. He kidnaps a young couple in the prime of their life together and forces them into a game of torment that slowly extinguishes their hopes for survival.
Chaney plays two roles: mad scientist Arthur Lamb and Lamb's "experiment", known only as the Ape Man. This hideous creature was the result of Lamb's attempts to transplant animal glands into human beings. A lost film.