Two college friends, now in their thirties, admire each others' lives and feel trapped in their own. Wes, tied to a demanding career and responsibilities to family, extends a work trip to drag his dispirited artist friend Luke to find Luke's "one that got away."
A transgender woman takes an unexpected journey when she learns that she had a son, now a teenage runaway hustling on the streets of New York.
The brief life of Jean Michel Basquiat, a world renowned New York street artist struggling with fame, drugs and his identity.
The story of three women searching for more potent, meaningful lives. Each is alive at a different time and place, all are linked by their yearnings and their fears. Their stories intertwine, and finally come together in a surprising, transcendent moment of shared recognition.
Wyatt and Billy, two Harley-riding hippies, complete a drug deal in Southern California and decide to travel cross-country in search of spiritual truth.
Heroin addict Mark Renton stumbles through bad ideas and sobriety attempts with his unreliable friends --Sick Boy, Begbie, Spud and Tommy. He also has an underage girlfriend, Diane, along for the ride. After cleaning up and moving from Edinburgh to London, Mark finds he can't escape the life he left behind as Begbie and Sick Boy come knocking.
People in the future live in a totalitarian society. A technician named THX 1138 lives a mundane life between work and taking a controlled consumption of drugs that the government uses to make puppets out of people. As THX is without drugs for the first time he has feelings for a woman and they start a secret relationship.
The drug-induced utopias of four Coney Island residents are shattered when their addictions run deep.
Narcotics Sergeant Nick Tellis, on leave after a trauma, is called back to investigate the murder of fellow undercover operative Michael Calvess, joined by the victim's unpredictable and brutal ex-partner, Henry Oak. Working together in the back alleys of Detroit, Tellis and Oak delve into a dark investigation that leads them to uncover shocking secrets and question the corruption and morality within the department, encountering unorthodox methods and a brutal truth about Calvess's death.
A young man losses the love of his life. Filled with depression and feeling dead inside will he make it? Can he move on?
When Albers takes his drug-addicted opera star sister Gerda to a sanitarium, they both become targets of slimy dope peddler Peter Lorre, who fears that Gerda will blow the whistle on him. Lorre kidnaps the woman, leading Albers on a frantic chase.
One man's love is personified in superhero form inside the mind of his drug addicted girlfriend as she goes through withdrawal.
Vincent LaMarca is a dedicated and well-respected New York City police detective who has gone to great lengths to distance himself from his past, but then makes the terrible discovery that his own son has fallen into a life of crime.
A departing professor gathers his closest colleagues for an intimate farewell, but the night takes an unexpected turn when he shares a stunning secret about his past. As the conversation unfolds, skepticism and curiosity collide, challenging everything they thought they knew about history, science, and belief.
Marie Heurtin is born both blind and deaf. Sister Marguerette wins her trust and teaches her how to express herself.
Eli Johnson struggles through high school challenged by his self-loathing and the pressure to be "normal". The recent passing of his mother due to terminal cancer leaves Eli and his father disconnected and in the dark. Bullied by his peers, Eli turns to prescription drugs to cope with his suicidal thoughts. Falling hopelessly for the popular Addison McKnight, he looks to his love for her as an escape out of his deep depression.
After her widowed father dies, deaf teenager Dot moves in with her godparents, Olivia and Paul Deer. The Deers' daughter, Nina, is openly hostile to Dot, but that does not prevent her from telling her secrets to her silent stepsister, including the fact that she wants to kill her lecherous father.
In his delirium from his return from war, Francesco Bernardone goes back in his memories to the days when he lived for parties and carnal pleasures. He slowly recovers, but after the illness he is no longer the Francesco that everybody knew. Instead of spending hours in taverns, he meditates on the beauty of God's creatures, soon renouncing his riches and his family with plans to rebuild an abandoned church and his life.
The story about the relationship between a manic depressive man, Mr. Jones, and the female doctor who takes more than a professional interest in his treatment.