Two childhood friends from South Boston turn to crime as a way to get by, ultimately causing a strain in their personal lives and their friendship.
After breaking up with his childhood love Paro, Dev finds solace in drugs and alcohol. He soon bumps into Leni, a prostitute, and falls for her.
Rick (Rutger Hauer), a disaffected sailor turned hard drinking womanizer, returns home from six months at sea to find his wife (Corrigan), whom he was deeply in love, has unexpectedly left him and is now a junkie whore. Devastated, he tries to ease his pain with booze and cheap thrills. His wife's best friend (Dagmar Lassander) makes a move on him, and when he spurns her (after scewing her first, naturally) she plots her revenge. She does so in an ingenious way, by exploiting a fantasy woman of his, but her plan backfires with tragic consequences.
Two estranged brothers, one a drug addict, the other, a schizophrenic, struggle to face their demons in the streets of Baltimore.
Einar is an addict who has just abandoned his wife and five-year-old daughter. While struggling to detox at his lodge near the ocean, Einar is harassed by a stranger.
Portland, Oregon, 1971. Bob Hughes is the charismatic leader of a peculiar quartet, formed by his wife, Dianne, and another couple, Rick and Nadine, who skillfully steal from drugstores and hospital medicine cabinets in order to appease their insatiable need for drugs. But neither fun nor luck last forever.
The mostly true story of the legendary "worst director of all time", who, with the help of his strange friends, filmed countless B-movies without ever becoming famous or successful.
In 1973, 15-year-old William Miller's unabashed love of music and aspiration to become a rock journalist lands him an assignment from Rolling Stone magazine to interview and tour with the up-and-coming band, Stillwater.
"Popeye" Doyle travels to Marseilles to find Alain Charnier, the drug smuggler that eluded him in New York.
A New York press agent must scramble when his major client becomes embroiled in a huge scandal.
After getting into a car accident while drunk on the day of her sister's wedding, Gwen Cummings is given a choice between prison or a rehab center. She chooses rehab, but is extremely resistant to taking part in any of the treatment programs they have to offer, refusing to admit that she has an alcohol addiction.
In 1965, a young woman with dreams of becoming a writer has a son at the age of 15 and struggles to make things work with the drug-addicted father.
When the trail goes cold on a murder investigation of a policeman, an undercover narcotics officer is lured back to the force to help solve the case.
Erre, a teenager that lives with his uncle, his aunt and an almost absent sister, is erased from the roster on his school. From then on, he just wanders in places where the strange is barely hidden under an imitation of the ordinary.
When the strain of tragedy was too much for a young couple in Appalachia, prescription pills became the medicine to ease the pain.
Sin and Illy have a plan: on a Greek island they want to get 'clean' on their own. But the intention of the two girls fails already on the way to the airport. Finally Sin realizes she has to go the way out of heroin addiction all alone.
An urgent phone call pulls a Yale Law student back to his Ohio hometown, where he reflects on three generations of family history and his own future.
While investigating a young nun's rape, a corrupt New York City police detective, with a serious drug and gambling addiction, tries to change his ways and find forgiveness.
After a friend overdoses, Spoon and Stretch decide to kick their drug habits and attempt to enroll in a government detox program. Their efforts are hampered by seemingly endless red tape, as they are shuffled from one office to another while being chased by drug dealers and the police.
Noah, an engineer high on antidepressants since a trauma, meets Lohan during a road trip. They will share a too-good-to-be-true love story.