Johnson, a pharmacist, makes an illicit traffic in cocaine and morphine, which he cleverly sells through his drug counter to a select clientele. In his richly furnished office, the head of the Kurson Chemical Company counts the receipts of Kurson Consumption Cure, a patented drug that contains a large amount of morphine.
Jim Blake, the playboy son of a New York millionaire, heads west to prove himself a man. He goes to work on his father's ranch in Wyoming, and eventually wins over the locals by turning the tables on a town bully and trying to collect damages from a railroad magnate, whose trains have killed many of the Blake ranch's cattle. When the railroad refuses to pay, Jim comes up with a plan that will make them pay far more than they originally had to. Problems arise when he falls in love with Alice, the railroad magnate's daughter.
A college graduate returns West after ten years in the East to her home in Sulfur Springs. Virginia's mother, the owner of a rooming house has turned hard and uncaring in her absence and the girl finds comfort in her friendship with Ross Cavanagh, a forest ranger. The latter runs afoul of cattle baron Sam Gregg, who resents a new tax on cattle grazing on government land.
Homesteaders battle a cattle baron, who is trying to drive them off the lands they have settled on so his cattle will be able to graze on it.
In an early California settlement, Juanita, a dance hall queen of Castilian ancestry, knifes her lover, Jim Brandt, the dance hall owner, when she catches him embracing a new dancer.
On the American frontier in the last decades of the 19th century, Billie is a female cowboy who fights a series of bad men in this film serial.
A lost film. Teddy Drake is a pleasure-seeking aristocrat who ends up expelled from his exclusive Fifth Avenue club for playing practical jokes and other rambunctious antics. He decides to reform his selfish ways and boards a train heading heading for the Southwest.
Rustler Pete Sontag kidnaps Merlin Warner after he kills her father. Pete, a drug smuggler who uses his saloon as a front, coerces Merlin though beatings to become the dancer Mexicali Mae. She meets and falls in love with morphine addict Joe Blanchard but Pete frames Joe for a murder that he committed, forcing Mae to hide Joe in a homestead in the hills. After many struggles, Joe is cured of his addiction and proposes to Mae. She accepts, but when his mother and fiancée Eleanor arrive, they offer her money to leave, Mae refuses the money but becomes convinced that she is not good enough for Joe and writes to him that she is returning to the saloon. Joe learning of his mother’s plot arrives at the saloon and in the resultant fight Pete is killed. Mae and Joe are reconciled.
Trying to trick Ma (Lydia Knott) and Mary Winters (Allene Ray) into selling their rundown ranch, which will be in the path of a future railroad, Underwood (Charles K.French) hires Keno Creager (Albert Smith) to impersonate Jimmy Winters, not seen by his mother and sister for many years.
Francelia Billington and Dorothy Gish battle outlaw Ralph Lewis out on the range with assistance from ranch foreman Donald Crisp.
The plot of this silent western short is unknown and it is presumably lost.
In the Old West Charles Garvin and Clarice Winslow are happily engaged. One day artist, Ed Gardner arrives seeking lodging and is welcomed into Clarice's home, where he meets the young cowboy. However, when Charles must depart for a round-up, Ed begins to charm Clarice, who seems amused by his company and a triangle develops.
A lost film. As described in a film magazine Exhibitors Herald on March 16, 1918: "a forest ranger known only as Headin' South (Fairbanks) goes forth in search of Spanish Joe (Campeau), a Mexican responsible for most of the treachery and outlawry along the U.S.-Mexican boarder. Headin' South gains quite a reputation as he goes along and finally believes himself worthy of joining Joe's band. in a whirlwind finish in which Joe is captured, Headin' South meets one of Joe's near victims (MacDonald) and falls in love with her."
A western settlement of pioneer descendants is threatened with the loss of its water supply through the encroachments of nearby townspeople.
Jeanne La Roche lives alone with her brother in the great northwestern country. Jacques is a ne'er-do-well and has fallen under the suspicion of the mounted police, two of whom are dispatched to arrest him for robbery. The stolen goods are found in his home. Jeanne is too young to be left in their lonely cabin, so she is taken to the post, where the wife of the proprietor welcomes her and gives her a home. Several years later, Donald McLean wins her for his wife. Meantime Jacques escapes from prison, eludes his pursuers and takes refuge in McLean's home.
Deputy Sheriff Martin of Arizona is in love with Lola a waitress at the Gold Dollar restaurant. However, complications arise when Martin encounters James Kinney, a wanted murderer working under an assumed name in the local mine. Deputy Martin discovers that Kinney is also interested in Lola, fueling a rivalry between the two men. During a mine accident, Kinney is placed in a dangerous situation and Martin must decide whether to act on his personal feelings or uphold his duty as a lawman.
Miner Jim Mann is indifferent to the new baby and sees him as nothing more than an additional burden. His wife Lucy looks after the baby and is unable to help much with the work, and Jim's dinner is often late. He grows to dislike the child and refuses to hold or pet him. Dawson, another miner, and his wife and their small baby occupy the cabin on the adjacent claim.
Mollie Owens, engaged to sheriff’s deputy Dick Calvert, is taken captive by outlaw Monk Turgis and imprisoned in the "death cabin” so called because everyone shunned it after of two mysterious murders were committed there. Turgis and his friend try to scare money out of Mollie's mother, but Dick sets out on their trail. He sees one of them enter the cabin and immediately investigates.
Vic Stanley, a wandering cowboy, is found by Clint Taggart and his daughter, Amy, after he has escaped from a band of rustlers. Upon recovering his sight from a desert sandstorm, he sees and falls in love with Amy and becomes resolute in his decision to uncover the identity of the rustlers and particularly their leader, "The Eagle." Though blind during his capture, he nevertheless recognizes the voice of The Eagle in McElroy, a leading banker. After another escape from the gang, Vic manages to save Taggart and Amy from The Eagle's sticky clutches, exposes their operation, and proceeds on course with Amy.
Gold miner Edd Denmeade loves Lucy Watson, the sister of the official mining claim recorder. Denmeade suspects Watson of killing his father, who after a poker game was shot by a gambler "who shuffles with one hand." The real murderer, Sam Spralls, has convinced Watson that he killed Denmeade and threatens to expose him unless Watson assigns him all the gold claims. Spralls assembles a band of killers to jump the claims when Watson complies. Eventually, Denmeade learns the identity of the killer when he sees Spralls shuffle a deck of cards. He forms a vigilante party and rids the community of Spralls and his gang.